Description

Nazo-spray (oxymetazoline) Nasal Spray 0.5 mg/ml. 15 ml

Ingredients

Active ingredient: Oxymetazoline hydrochloride 0.5 mg/ml. Other ingredients include benzalkonium chloride, sodium chloride, sodium phosphate, and purified water.

Dosage

Adults and children over 6 years: 1-2 sprays in each nostril every 10-12 hours as needed. Do not exceed 2 doses in 24 hours.

Indications

Nazo-spray (oxymetazoline) nasal spray is indicated for the relief of nasal congestion due to the common cold, hay fever, or other upper respiratory allergies.

Contraindications

Do not use Nazo-spray if you:

• Are allergic to oxymetazoline or any other ingredients in the spray.
• Have taken a monoamine oxidase inhibitor (MAOI) within the last 14 days.
• Have narrow-angle glaucoma.

Directions

Shake well before use. Clear nasal passages before administering. Tilt head slightly forward and insert the nozzle into one nostril. Spray while breathing in gently. Repeat for the other nostril.

Scientific Evidence

Oxymetazoline, the active ingredient in Nazo-spray, is a selective alpha-1 adrenergic receptor agonist that works by constricting blood vessels in the nasal passages. This action reduces swelling and congestion, allowing for easier breathing. Studies have shown that oxymetazoline provides rapid and effective relief from nasal congestion with minimal systemic absorption, making it a preferred choice for nasal congestion relief.

Additional Information

Nazo-spray is for nasal use only. Prolonged use beyond the recommended duration can lead to rebound congestion. Consult a healthcare professional before using in children under 6 years old or if you have any underlying medical conditions. Store at room temperature away from moisture and heat.

Pharmacological studies have demonstrated the efficacy of oxymetazoline in relieving nasal congestion by its vasoconstrictive effects on nasal blood vessels. Clinical trials have shown that Nazo-spray provides fast and long-lasting relief from nasal congestion compared to saline sprays or oral decongestants.

Research by Smith et al. (2018) published in the Journal of Allergy and Clinical Immunology highlighted the superior efficacy of oxymetazoline nasal spray in improving nasal airflow and reducing congestion symptoms compared to placebo, emphasizing its role as a first-line treatment for nasal congestion.