Nebido solution for injection 250 mg/ml. 4 ml. №1 vial

Description

Nebido composition
One ampoule contains: 1000 mg of testosterone undecaonate. Additional ingredients include benzyl benzoate and castor oil.

Release form
The drug is produced in the form of an injectable oil liquid, in glass ampoules of 4 ml.

Pharmacological properties
Nebido is an androgenic agent. It is used to treat hypogonadism (insufficient production of sex hormones), both primary and secondary. The active substance – testosterone, is an ester of testosterone, the main sex hormone in men, which is responsible for the development of the genitals and secondary sexual characteristics. Testosterone is also involved in metabolic processes in the skin, muscles, central nervous system, bone tissue, bone marrow, liver and kidneys. It is produced by the testes and partly by the adrenal glands. Insufficient testosterone production leads to decreased libido, muscle weakness, decreased performance, and many other adverse effects. When ingested, testosterone undecaonate breaks down predominantly into dihydronestosterone. Only a small part of the substance is divided into estrogens, thereby reducing the risk of saturation with female hormones and the development of gynecomastia. It is metabolized mainly (90%) through the genitourinary system and about 5% through the intestines. The drug helps to increase testosterone levels on the second day after use. In cases of hypogonadism – 7-14 days.

Indications for use
Nebido is prescribed for hypogonadism (a deficiency in the production of male hormones), both in the primary and secondary forms.

Contraindications
The tool has a number of contraindications for use, among them:

• prostate cancer (androgenic etiology);
• breast cancer in men (androgenic etiology);
• increased blood calcium levels;
• neoplasms in liver tissue (past or present);
• increased sensitivity to drug components.
• minority (fraught with growth arrest);
• female.

It is necessary to use the drug with caution in patients with apnea syndrome (respiratory arrest during sleep).

Children
It is not used in pediatrics.

Pregnancy and breastfeeding period
The drug is not intended for use by women.

Mode of application
An important point when using Nebido is a warning that you should not inject the drug intravenously or allow it to enter the vessels. This can cause blockage of blood vessels in the lungs. Only slow, intramuscular injection is allowed. The dosage is calculated based on the data obtained from the testosterone production tests. On average, the dose can be 1 ampoule (4 ml), every 10-15 weeks. The minimum possible interval between the introduction is 6 weeks. While taking the drug, it is necessary to monitor the testosterone level after each injection. Based on the testosterone levels in the body, the interval between hormone injections can vary. The higher the testosterone level, the longer the breaks between meals should be.
During the reception of the drug, it is necessary to be regularly examined for the presence of disorders of the prostate gland.

Overdose
Exceeding the permissible doses of the drug is fraught with an increase in the level of testosterone in the body, with all the ensuing consequences. Treatment: adjusting the dosage and intervals of administration of the agent.

Adverse reactions
During drug therapy, the following adverse events may develop:

• pain at the injection site;
• rash at the injection site;
• violation of the stool;
• nausea;
• vomiting;
• headache;
• dizziness;
• failures in respiratory function;
• sweating;
• increased appetite;
• redness of the skin;
• tremor;
• irritability
• depression;
• delay in urination;
• pain in muscles and joints;
• pain in the mammary glands, hykenomastia;
• the development of neoplasms of a malignant and benign nature (in isolated cases);
• prostatitis;
• violation of sexual desire;
• pain in the testicles.

Storage conditions
The drug must be stored away from children at a temperature not exceeding 25 degrees.
When stored properly, the shelf life is 3 years.