Description

Nebido Solution for Injection 250 mg/ml. 4 ml. №1 Vial

Ingredients:

Each ml contains 250 mg of testosterone undecanoate in oily solution.

Dosage:

The usual dose is 1000 mg (4 ml) injected every 10-14 weeks.

Indications:

Nebido is indicated for testosterone replacement therapy in adult males for conditions associated with a deficiency or absence of endogenous testosterone.

Contraindications:

Do not use Nebido if you have prostate cancer, breast cancer, or known or suspected hypersensitivity to the active substance or any of the excipients.

Directions:

Administer Nebido by deep intramuscular injection into the gluteal muscle.

Scientific Evidence:

Nebido, with its active ingredient testosterone undecanoate, has been extensively studied for its efficacy in testosterone replacement therapy. Clinical trials have shown that Nebido provides sustained testosterone levels over an extended period, leading to improvements in symptoms associated with low testosterone levels.

Research published in the Journal of Clinical Endocrinology & Metabolism demonstrated that Nebido injections every 10-14 weeks effectively maintained testosterone levels within the normal range in hypogonadal men, resulting in improvements in libido, mood, and overall quality of life.

Additional Information:

• Storage: Store below 25°C. Do not freeze. Protect from light.
• Side Effects: Common side effects include acne, injection site pain, and increased hematocrit levels.
• Precautions: Monitor prostate-specific antigen (PSA) levels during therapy. Use with caution in patients with cardiovascular disease.

Pharmacologically, Nebido acts by replacing the deficient testosterone in the body, restoring normal physiological functions that require adequate testosterone levels. It interacts with androgen receptors in various tissues to exert its effects, such as promoting secondary sexual characteristics and maintaining muscle mass and bone density.

Compared to other testosterone replacement therapies, Nebido’s long-acting formulation offers the advantage of less frequent dosing, leading to improved patient compliance and convenience. This has been supported by studies showing that Nebido injections every 10-14 weeks are as effective as more frequent testosterone injections in maintaining therapeutic levels.