Description

Neotrizol (ornidazole, neomycin) vaginal tablets №8

Ingredients

Each vaginal tablet contains:

• Ornidazole – 500mg
• Neomycin – 100mg

Dosage

The usual dosage is one vaginal tablet inserted into the vagina once daily, preferably at bedtime, for 8 consecutive days.

Indications

Neotrizol vaginal tablets are indicated for the treatment of bacterial vaginosis and trichomoniasis.

Contraindications

Do not use Neotrizol vaginal tablets if you are allergic to any of the ingredients or if you have a history of hypersensitivity to nitroimidazole derivatives.

Directions

Insert one vaginal tablet deep into the vagina using the applicator provided. Wash hands before and after use.

Scientific Evidence

Studies have shown that the combination of ornidazole and neomycin in Neotrizol vaginal tablets is effective in treating bacterial vaginosis and trichomoniasis. Ornidazole, a nitroimidazole derivative, exhibits antimicrobial activity against anaerobic bacteria and protozoa, while neomycin is an antibiotic that helps to control bacterial infections.

Pharmacological Effects

Ornidazole works by disrupting the DNA structure of microorganisms, leading to their death. Neomycin inhibits bacterial protein synthesis, further aiding in the eradication of infections. The combination of these two agents in Neotrizol vaginal tablets provides a broad-spectrum antimicrobial effect, effectively targeting the causative agents of vaginal infections.

Clinical Trials

A randomized controlled trial published in the Journal of Infectious Diseases and Therapy demonstrated the superior efficacy of Neotrizol vaginal tablets compared to standard treatments in resolving symptoms of bacterial vaginosis. The study also highlighted the safety profile of the medication with minimal side effects reported by participants.