Neurocitin solution for infusions 100 ml. vial №1

Description

Neurocitin composition
Main active ingredients: citicoline, sodium chloride, potassium chloride, calcium chloride diibrate, sodium lactate.
Excipients included in the preparation: water for injection.
1 ml of the drug contains 10 mg of citicoline, 6 mg of sodium chloride, 0.4 mg of potassium chloride, 0.27 mg of calcium chloride, 3 ml of sodium lactate.

Release form
Available in the form of an infusion solution, in 100 ml vials.

Pharmacological properties
Neurocitin belongs to the drug group of psychostimulant nootropics, the citicoline class, which is used to improve the cognitive functions of the brain.
The main active ingredient is citicoline, a substance that is analogous to a natural nucleoside, a phosphatidylcholine precursor. Also related to other phospholipids that are part of cell membranes.
Studies have shown that citicoline has the ability to improve cerebral circulation, increases the efficiency of oxygen supply to brain cells. As a result, cerebral metabolism is normalized, the work of the brain improves.
Citicoline is also an active donor of organic choline compounds, which are used in the metabolic process in the synthesis of acetylcholines (neurotransmitters, thanks to which neuromuscular transmission of nerve impulses is carried out).
It protects, restores and improves the functioning of the cell membranes of neurons, produces a decongestant effect on the brain, and prevents the release of free radicals. The use of the drug helps to reduce the recovery period after traumatic brain injuries, strokes, and other disorders of the brain.
Lactate, also a part of the preparation, helps to alkalinize the solution.

Indications
Neurocitin is used to treat diseases associated with brain dysfunction. In particular, they are prescribed for:

• cognitive, sensory, movement disorders;
• in the acute phase of cerebral circulation disorders (strokes);
• therapy of the consequences of cerebrovascular accident;
• traumatic brain injury, both in the acute and in the recovery period;
• with encephalopathy of various origins, degenerative diseases of the brain;
• prolonged coma;
• complications after surgery on the brain (edema);
• parkinsonism (can be used in combination with anticholinergics, if it is impossible to prescribe levodopa).

Contraindications
The drug in question is contraindicated for use in cases where the patient has severe hypersensitivity (allergy) to the main or one of the auxiliary components.
It is also contraindicated to use with increased tone of the parasympathetic nervous system.

Application during pregnancy and lactation
This drug can be used in the treatment of pregnant women only with careful weighing of the benefit / harm ratio.
If it is necessary to take the drug during breastfeeding, then during treatment, lactation should be suspended.

Method of administration and dosage
Neurocitin solution is administered intravenously as an infusion.
Recommended dosages are from 500 to 2 thousand mg per day (50-200 ml of solution). The prescribed dose depends on the severity of the symptoms, the severity of the course of the disease, and the individual reaction to the drug.
It can be administered intravenously as a jet (speed – 3-5 minutes) and drip (30-60 drops per minute).
Treatment regimen for acute conditions:

• the first 14 days – from 500 to 1 thousand mg of citicoline, 2 times a day, intravenously;
• starting from day 15 – from 500 to 1 thousand mg, 2 times a day, intramuscularly.

The maximum daily dose is 2 thousand mg of citicoline per day.
The duration of the course of treatment is 12 weeks.
Elderly patients, as well as patients with hepatic and / or renal insufficiency, do not need dosage adjustment.

Overdose
Overdose has not been recorded at the moment.
In case of accidental overdose, theoretically, it is possible to increase the side effects.
In this case, symptomatic therapy is recommended.

Side effects
Possible side effects:

• allergic reactions – rash, itching, urticaria, hyperemia, exanthema, purpura, Quincke’s edema (angioedema), anaphylactic shock;
• severe headache, vertigo, hallucinations;
• arterial hypertension, arterial hypotension, tachycardia;
• dyspnea;
• nausea, vomiting, diarrhea;
• chills, pain at the injection site.

If these side effects or not described in this manual appear, you should consult your doctor.

Storage conditions and periods
The shelf life is up to 2 years.
The storage temperature should be no more than 30 ° C.