Description

Nifedipin (Nifedipine) Coated Tablets 0.01 g. №50

Ingredients

Active ingredient: Nifedipine 0.01 g per tablet.

Dosage

Dosage: The usual dose is 1 tablet three times a day. Dosage may vary based on individual medical conditions.

Indications

Indications: Nifedipine is indicated for the treatment of hypertension and chronic stable angina.

Contraindications

Contraindications: Do not use Nifedipine if you have hypotension, acute myocardial infarction, or a known hypersensitivity to the drug.

Directions

Directions: Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.

Scientific Evidence

Nifedipine, a calcium channel blocker, has been extensively studied for its efficacy in managing hypertension and angina. Research published in the Journal of Clinical Pharmacology demonstrated that nifedipine effectively reduces blood pressure by relaxing blood vessels, thus improving blood flow and lowering the workload on the heart.

Additional Information

Nifedipine coated tablets are formulated to provide a controlled release of the medication, ensuring a steady and sustained effect over time. It is important to follow the prescribed dosage and not exceed the recommended amount to avoid adverse effects.

Pharmacological Effects: Nifedipine works by inhibiting the influx of calcium ions into cardiac and smooth muscle cells, leading to vasodilation and decreased peripheral vascular resistance. This mechanism helps in reducing blood pressure and relieving angina symptoms.

Clinical Trials: Clinical trials have shown that nifedipine is effective in lowering blood pressure and improving exercise tolerance in patients with angina pectoris. A study published in the American Journal of Cardiology reported significant reductions in blood pressure and angina episodes with nifedipine treatment.