Description

Nifuroxazid (Nifuroxazide) Coated Tablets 200 mg. №20

Ingredients:

Each coated tablet contains 200 mg of Nifuroxazid as the active ingredient.

Dosage:

The usual dosage for adults is 800 mg per day, divided into four doses. Consult a healthcare professional for appropriate dosing in children.

Indications:

Nifuroxazid is indicated for the treatment of acute infectious diarrhea. It works by inhibiting the growth of bacteria in the intestines.

Contraindications:

Do not use Nifuroxazid if you are allergic to it or if you have severe liver disease. Consult your doctor before use if you are pregnant or breastfeeding.

Directions:

Take Nifuroxazid as directed by your healthcare provider. It is usually taken with food. Do not crush or chew the tablets.

Scientific Evidence:

Nifuroxazid has been studied extensively for its efficacy in treating infectious diarrhea. Research published in the “Journal of Pediatric Gastroenterology and Nutrition” showed that Nifuroxazid significantly reduced the duration of diarrhea in children compared to a placebo.

Additional Information:

It is important to complete the full course of Nifuroxazid as prescribed, even if symptoms improve. If you experience severe or persistent diarrhea, contact your healthcare provider. Store the tablets at room temperature away from moisture and heat.

Pharmacological Effects: Nifuroxazid is a nitrofuran derivative with broad-spectrum antibacterial activity against enteric pathogens. It acts by interfering with the bacterial cell wall synthesis, leading to bacterial cell death. The drug is minimally absorbed from the gastrointestinal tract, exerting its effects primarily in the intestines.

Clinical Trials: In a randomized controlled trial published in the “European Journal of Clinical Pharmacology,” Nifuroxazid demonstrated superior efficacy in reducing the frequency and duration of diarrhea episodes compared to traditional anti-diarrheal agents. The study highlighted the safety and effectiveness of Nifuroxazid in the management of acute infectious diarrhea.