Description

No-shpa (Drotaverine) Ampoules 20 mg/ml. 2 ml. №25

Ingredients

Active ingredient: Drotaverine hydrochloride 20 mg/ml.

Dosage

Dosage: The usual dose is 40-80 mg per day, divided into 3-4 doses.

Indications

Indications: No-shpa is indicated for the treatment of smooth muscle spasms in various conditions such as biliary colic, renal colic, dysmenorrhea, and irritable bowel syndrome.

Contraindications

Contraindications: No-shpa is contraindicated in patients with hypersensitivity to drotaverine, severe hepatic or renal impairment, and certain heart conditions.

Directions

Directions: No-shpa is administered intramuscularly or intravenously. It should be administered slowly to avoid irritation at the injection site.

Scientific Evidence

Drotaverine, the active ingredient in No-shpa, exerts its pharmacological effects by inhibiting phosphodiesterase enzyme and causing relaxation of smooth muscles. This action results in the dilation of blood vessels and decreased spasms, leading to pain relief.

Several clinical studies have demonstrated the efficacy of drotaverine in the treatment of various smooth muscle spasms. A study published in the Journal of Pain Research showed that drotaverine was effective in relieving biliary colic pain with a rapid onset of action and good tolerability.

Additional Information

• No-shpa is well-tolerated with minimal side effects such as dizziness or gastrointestinal disturbances.
• It is important to follow the prescribed dosage and not exceed the recommended daily dose to avoid adverse effects.