Description

Noliprel Bi-forte Coated Tablets 10/2.5 mg. №30

Ingredients:

Each coated tablet contains 10 mg of perindopril arginine and 2.5 mg of indapamide.

Dosage:

The usual dose is one tablet taken once daily, preferably in the morning before a meal.

Indications:

Noliprel Bi-forte is indicated for the treatment of essential hypertension in patients whose blood pressure is not adequately controlled with perindopril alone.

Contraindications:

Do not use Noliprel Bi-forte if you are allergic to perindopril, indapamide, or any other ingredients in the product.

Directions:

Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.

Scientific Evidence:

Noliprel Bi-forte combines the antihypertensive effects of perindopril, an ACE inhibitor, with the diuretic properties of indapamide. Studies have shown that this combination is more effective in lowering blood pressure compared to monotherapy with either drug alone. Research published in the European Heart Journal demonstrated that the use of perindopril-indapamide combinations significantly reduced the risk of cardiovascular events in hypertensive patients.

Additional Information:

It is important to monitor electrolyte levels regularly, especially potassium, when using Noliprel Bi-forte due to the diuretic component. This medication may cause dizziness, so caution is advised when driving or operating machinery. Consult your healthcare provider before starting Noliprel Bi-forte, especially if you have kidney problems or are pregnant.

Overall, Noliprel Bi-forte is a well-tolerated and effective treatment for hypertension, supported by clinical trials and research. It offers a convenient once-daily dosing regimen and a dual mechanism of action that targets both blood pressure regulation and cardiovascular protection.