Description

Normaze (lactulose) oral syrup 200 ml. vial

Ingredients

Active ingredient: Each 15 ml of Normaze oral syrup contains lactulose 10 g.

Dosage

Dosage: The usual adult dose is 15-30 ml daily, adjusted according to individual response.

Indications

Indications: Normaze oral syrup is indicated for the treatment of constipation and hepatic encephalopathy.

Contraindications

Contraindications: Do not use Normaze oral syrup in patients with galactosemia or a history of hypersensitivity to lactulose.

Directions

Directions: Shake well before use. Take with water or fruit juice. It may take 24 to 48 hours to produce a bowel movement.

Scientific Evidence

Scientific evidence: Studies have shown that lactulose, the active ingredient in Normaze oral syrup, is effective in treating constipation by increasing colonic motility and promoting the growth of beneficial gut bacteria.

Additional Information

Storage: Store at room temperature away from moisture and heat. Keep out of reach of children.

Pharmacological Effects: Lactulose is a synthetic disaccharide that is not absorbed in the small intestine but is fermented by gut bacteria in the colon. This fermentation process leads to an increase in osmotic pressure and acidification of the colonic contents, which softens the stool and promotes bowel movements.

Clinical Trials: Clinical trials have demonstrated the efficacy of lactulose in the management of chronic constipation and hepatic encephalopathy. In a randomized controlled trial published in the Journal of Gastroenterology, lactulose was found to significantly improve stool frequency and consistency in constipated patients compared to placebo.