$19.00
Normomed is prescribed to people with a reduced or normal immune status for viral infections.
Description
Normomed composition and form of release
The active ingredient of Normomed is inosine pranobex. Also, the preparation contains excipients: magnesium stearate, povidone, potato starch.
Normomed is produced in the form of tablets (500 mg).
Pharmacological properties
Normomed is an antiviral medicine. Its active substance has a direct antiviral and immunity modulating effect. Its effect is due to the ability to bind to the ribosomes of cells affected by the virus, slowing down the production of viral i-RNA and inhibiting the replication (self-reproduction) of DNA and RNA viruses. It also inhibits the formation of interferons. The immunomodulatory effect is due to its effect on T-lymphocytes and an increase in the absorbing (phagocytic) activity of macrophages. Normomed enhances the differentiation (sorting) of pre-T-lymphocytes, stimulates the multiplication of immune cells (T-, B-lymphocytes), increases the activity of T-lymphocytes, normalizes the ratio between the populations of T-helpers and suppressors ( restores the CD4 / CD8 index). As a result of the complex effect of the drug on immunity, the viral load decreases, the production of immune cells is normalized, the production of its own interferons is activated, contributing to resistance to infections, and the rapid limitation of the focus of infection …
Indications
Normomed is prescribed to people with a reduced or normal immune status for viral infections: adenoviral infections, parainfluenza, influenza, other acute respiratory viral infections, bronchitis of viral origin, mumps, measles, herpes simplex (herpes of the skin of the hands, face , lips, mucous membranes of the mouth, eyes), subacute sclerosing panencephalitis (progressive damage to all brain tissues), genital herpes, infectious mononucleosis, chickenpox, shingles, cytomegalovirus, HPV (human papillomavirus), acute or chronic hepatitis B, recurrent ( constantly recurring) infections of the urinary system of the respiratory system …
Contraindications
The drug should not be used in people who do not tolerate pranobex, other components of this medication. Also, it is not prescribed for patients with kidney / liver failure, urolithiasis, gout, or hyperuricemia (elevated blood levels of uric acid).
Normomed is prescribed with caution to elderly patients, since there is a risk of developing hyperuricemia, hyperuricosuria (an increase in the level of uric acid in the urine).
Children
It is used in pediatrics for children from 1 year old.
Application during pregnancy and lactation
Due to the lack of research, it is not recommended to prescribe Normomed during these periods.
Method of administration and dosage
Normomed is taken orally (by mouth) at regular intervals, preferably after meals. Normomed tablet can be crushed, chewed or dissolved in a small volume of water (right before taking).
The duration of Normomed treatment is determined depending on the disease, the severity of its course, the frequency of relapses. The average duration of treatment with Normomed is 5-14 days. The treatment course can be repeated, if necessary, after a break of 7-10 days. Treatment with Normomed can last 1–6 months (intermittently). The maximum dose that an adult can take per day is 4 g (8 Normomed tablets).
The following doses and regimens for Normomed are recommended.
- For influenza, parainfluenza, other acute respiratory viral infections: adult patients – 2 tablets x 3-4 times / day, children – 50 mg / kg / day for three to four doses (course of 5-7 days). Treatment with Normomed can be continued or repeated if necessary after 7–8 days. To achieve maximum effectiveness, it is better to start taking Normomed with early symptoms of a cold or from the first day of the illness. Normomed is usually taken one to two days after the symptoms of colds disappear.
- With epidparotitis: 70 mg / kg / day in 3-4 divided doses (7-10 days).
- For viral bronchitis: adults are prescribed 1 g (2 tablets of Normomed ) x 3 times / day, children – 50 mg / kg in three to four doses (2-4 weeks).
- For aphthous (herpetic) stomatitis: adults are prescribed 1 g (2 Normomed tablets) x 4 times / day, children – 70 mg / kg / day for three to four (course 6-8 days) in the acute phase, then 1 g x 3 times / day, children – 50 mg / kg / day for three to four doses twice a week (course 6 weeks).
- For cytomegalovirus infection: 50 mg / kg / day for three to four doses (25-30 days).
- With Epstein-Barr infection: 50 mg / kg / day for 3-4 doses (8 days).
- For measles: 100 mg / kg / day in 3-4 divided doses (7-14 days).
- For herpes zoster, lip herpes: adults – 1 g (2 Normomed tablets) x 3-4 times / day, children – 50 mg / kg / day in three to four doses (10-14 days).
- For herpes of the genitals: in the acute period – 1 g (2 Normomed tablets) x 3 times / day for 5-6 days, during the period of remission (abatement) a maintenance dose is prescribed – 1 g (2 Normomed tablets) x 1 time / day course up to 6 months.
- With papillomavirus (genital warts): 1 g (2 Normomed tablets) x 3 times / day, treatment course – 14-28 days. When using simultaneously cryotherapy, CO2-laser therapy – 1 g (2 tablets) x 3 times / day for 5 days. Shown three courses at intervals of a month.
- With sclerosing panencephalitis (subacute): 50-100 mg / kg / day for 6 doses (after 4 hours) for 8-10 days. After a break (8 days), with a mild course, one or three additional courses are prescribed, with a severe one – up to nine courses.
- For hepatitis B: adults – 1 g (2 Normomed tablets) x 3-4 times / day for 15-30 days, then a maintenance dose is applied – 1 g (2 Normomed tablets) x 1 time / day for 2-6 months.
- In case of recurrent infections of the respiratory or urinary tract in people with weak immunity: adults – 1 g (2 Normomed tablets) x 3-4 times / day. The treatment course is from 2 weeks to 3 months. Children are prescribed a daily dose at the rate of 50 mg / kg for 3-4 doses in a course of 21 days (or 3 treatment courses for 7-10 days with intervals of 7-10 days).
To restore the immune system in individuals with a weakened immune status, the treatment course should last 3–9 weeks.
Overdose
Overdose cases are not described.
Drug overdose may be accompanied by an increase in the amount of uric acid in the blood / urine. In case of an overdose, gastric lavage with a probe and symptomatic treatment are performed.
Side effects:
- Nervous system disorders: fatigue, headache, feeling unwell, nervousness, dizziness, insomnia, or drowsiness.
- Digestive tract disorders: pain in the abdominal region, nausea, diarrhea (frequent and loose stools), constipation, lack of appetite.
- Skin changes: itching, redness, skin rashes, including hives.
- Immune system disorders: allergies, incl. angioneurotic edema (sharp swelling of the face, lips, tongue).
- Disorders of the liver, biliary tract: increased levels of alkaline phosphatase, transaminases (ALT, AST), urea nitrogen in the blood.
- Disorders of the musculoskeletal system: joint pain.
- Urinary tract disorders: An increase in the volume of urine excreted (polyuria).
Storage conditions and periods
Store Normomed in its original packaging at 15–25 ° C. Shelf life is 2 years.
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