Description

Normopres (captopril, hydrochlorothiazide) tablets №20

Ingredients

Active ingredients: Captopril, Hydrochlorothiazide

Dosage

Dosage: The usual recommended dose is 1 tablet daily, or as directed by a healthcare professional.

Indications

Indications: Normopres tablets are indicated for the treatment of hypertension in patients requiring dual therapy.

Contraindications

Contraindications: Do not use Normopres if you are allergic to any of the ingredients, have a history of angioedema related to previous treatment with ACE inhibitors, or if you are pregnant.

Directions

Directions: Take Normopres tablets orally with or without food, as directed by your doctor. Do not exceed the recommended dose.

Scientific Evidence

Normopres (captopril, hydrochlorothiazide) tablets have demonstrated efficacy in lowering blood pressure in clinical trials.

Studies have shown that the combination of captopril and hydrochlorothiazide effectively reduces blood pressure by different mechanisms of action. Captopril, an ACE inhibitor, works by blocking the conversion of angiotensin I to angiotensin II, leading to vasodilation and decreased blood pressure. Hydrochlorothiazide, a diuretic, promotes the excretion of sodium and water, further reducing blood volume and pressure.

Additional Information

Pharmacological Effects: The dual action of captopril and hydrochlorothiazide in Normopres tablets provides a synergistic effect in managing hypertension. Captopril helps relax blood vessels, while hydrochlorothiazide reduces fluid retention, collectively aiding in blood pressure control.

Clinical Trials: Clinical trials have shown that Normopres tablets are well-tolerated and effective in lowering blood pressure in patients with hypertension. Long-term studies have demonstrated sustained blood pressure control and a reduced risk of cardiovascular events with the use of this combination therapy.