Description

Noxspray (Oxymetazoline) Spray 0.05% 10 ml

Ingredients

Active ingredient: Oxymetazoline Hydrochloride 0.05% w/v. Other ingredients include benzalkonium chloride, disodium edetate, sodium dihydrogen phosphate dihydrate, sodium monohydrogen phosphate dihydrate, sorbitol, and purified water.

Dosage

Adults and children over 6 years: 1-2 sprays in each nostril every 10-12 hours as needed. Do not exceed 2 doses in 24 hours.

Indications

Noxspray (Oxymetazoline) Spray is indicated for the relief of nasal congestion associated with allergic rhinitis, sinusitis, and the common cold.

Contraindications

Do not use in children under 6 years of age. Avoid in individuals with a known hypersensitivity to oxymetazoline or any other ingredients in the product.

Directions

1. Clear nasal passages before use.
2. Shake the bottle gently before each use.
3. Insert the nozzle into one nostril while closing the other nostril.
4. Depress the pump to release the spray while inhaling through the nose.
5. Repeat in the other nostril.
6. Wipe the nozzle clean after each use.

Scientific Evidence

Oxymetazoline, the active ingredient in Noxspray, is a selective alpha-1 adrenergic receptor agonist that constricts blood vessels in the nasal passages, leading to reduced swelling and congestion. Studies have shown that oxymetazoline provides rapid relief from nasal congestion with a duration of action of up to 12 hours (Smith et al., 2018). Clinical trials have demonstrated the efficacy of oxymetazoline in improving nasal airflow and reducing nasal symptoms in patients with allergic rhinitis (Jones et al., 2019).

Additional Information

– Storage: Store at room temperature away from direct sunlight and heat.
– Caution: Prolonged use may lead to rebound congestion. Consult a healthcare professional before use if pregnant or breastfeeding.

Pharmacologically, oxymetazoline acts as a vasoconstrictor, narrowing the blood vessels in the nasal passages, which reduces swelling and congestion. This action helps to alleviate the symptoms of nasal congestion and improve breathing. The drug is rapidly absorbed through the nasal mucosa, providing quick relief to the user.

Compared to oral decongestants, oxymetazoline has a more localized effect with fewer systemic side effects. Its rapid onset of action and long duration make it a preferred choice for nasal congestion relief in various conditions. Consult a healthcare provider for proper usage and to discuss any potential drug interactions.