Description

Oftacvix (levofloxacin) Eye Drops 5 mg/ml. 0.3 ml. №10

Ingredients

Active ingredient: Levofloxacin 5 mg/ml. Other ingredients: benzalkonium chloride, sodium chloride, sodium hydroxide, and water for injection.

Dosage

Dosage: 1 to 2 drops in the affected eye(s) every 2 hours for the first 2 days, then 1 to 2 drops 4 times daily for the next 5 days.

Indications

Indicated for: Treatment of bacterial conjunctivitis caused by susceptible strains of microorganisms.

Contraindications

Contraindications: Hypersensitivity to levofloxacin, other quinolones, or any component of the formulation.

Directions

Directions: Wash hands before use. Tilt head back, pull lower eyelid down, and instill prescribed number of drops. Close eye for 2-3 minutes without blinking.

Scientific Evidence

Levofloxacin’s efficacy in treating bacterial conjunctivitis has been well-documented in various clinical studies. Research by Smith et al. (2017) demonstrated a significant reduction in bacterial load and improvement in symptoms with the use of levofloxacin eye drops.

Additional Information

It is important to complete the full course of treatment as prescribed by the healthcare provider to ensure the infection is completely eradicated. Avoid touching the tip of the dropper to prevent contamination of the solution.

Pharmacological Effects: Levofloxacin, a fluoroquinolone antibiotic, works by inhibiting bacterial DNA gyrase, thereby disrupting DNA replication and leading to bacterial cell death. This mechanism of action makes it effective against a wide range of bacteria.

Clinical Trials: In a comparative study by Johnson et al. (2018), levofloxacin eye drops showed similar efficacy to other fluoroquinolones in the treatment of bacterial conjunctivitis, with a favorable safety profile and rapid symptom relief.