Description

Ogrania (pregabalin) Capsules 75 mg

Ingredients

• Each capsule contains 75 mg of pregabalin.

Dosage

• The recommended dosage is as prescribed by a healthcare provider.

Indications

• Ogrania capsules are indicated for the management of neuropathic pain, fibromyalgia, and as an adjunctive therapy for adults with partial seizures.

Contraindications

• Do not use Ogrania capsules if you are allergic to pregabalin or any other ingredients in the product.

Directions

• Take Ogrania capsules orally with or without food as directed by your healthcare provider.

Mechanism of Action

Pregabalin, the active ingredient in Ogrania capsules, binds to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system. This binding reduces the release of excitatory neurotransmitters, modulating neuronal excitability and reducing pain signals.

Pharmacological Properties

Several clinical trials have demonstrated the efficacy of pregabalin in managing neuropathic pain, fibromyalgia, and partial seizures. For example, a study by Rosenstock et al. (2004) showed significant pain intensity reduction and improved sleep quality in diabetic neuropathy patients.

Side Effects

• Ogrania capsules may cause dizziness, drowsiness, and weight gain.
• Avoid alcohol consumption while taking this medication as it can exacerbate these side effects.

Precautions

• Consult your healthcare provider before using Ogrania capsules if you have a history of substance abuse or mood disorders.