Description

Otrivin (xylometazoline hydrochloride) Drops 0.05% 10 ml

Ingredients:

Active ingredient: Xylometazoline hydrochloride 0.05% w/v. Other ingredients include benzalkonium chloride, disodium phosphate dodecahydrate, sodium dihydrogen phosphate dihydrate, sorbitol, and purified water.

Dosage:

Adults and children over 12 years: 1-2 drops into each nostril 2-3 times daily. Do not exceed the recommended dosage.

Indications:

Otrivin Drops 0.05% are indicated for the relief of nasal congestion associated with hay fever, sinusitis, and colds.

Contraindications:

Do not use Otrivin Drops 0.05% if you are allergic to xylometazoline or any other ingredients in the product. Consult a healthcare professional before use if you have heart disease, high blood pressure, thyroid problems, diabetes, or prostate enlargement.

Directions:

For nasal use only. Tilt your head forward, insert the dropper into the nostril, and squeeze the bottle while inhaling gently. Repeat for the other nostril. Do not use for more than 7 consecutive days.

Scientific Evidence:

Xylometazoline hydrochloride, the active ingredient in Otrivin Drops 0.05%, is a selective alpha-adrenergic agonist that constricts blood vessels in the nasal mucosa, leading to decreased swelling and congestion. Studies have shown its effectiveness in providing rapid relief from nasal congestion without significantly affecting systemic blood pressure.

Additional Information:

Otrivin Drops 0.05% should not be used in children under 12 years of age without medical advice. Prolonged use may lead to rebound congestion. If symptoms persist, discontinue use and consult a healthcare professional.

Pharmacological studies have demonstrated that xylometazoline hydrochloride acts locally on alpha-adrenergic receptors in the nasal mucosa, resulting in vasoconstriction and reduced nasal blood flow. This action helps alleviate congestion and improve nasal breathing.

Clinical trials comparing xylometazoline with other nasal decongestants have shown it to be equally effective in providing relief from nasal congestion with a rapid onset of action. Its use is associated with minimal side effects when used as directed.