Description

Oxaliplatin Concentrate for Infusions 5 mg/ml. 10 ml. (50 mg.) №1

Ingredients:

Each ml contains 5 mg of oxaliplatin. Other ingredients include lactose monohydrate, water for injections, and sodium hydroxide for pH adjustment.

Dosage:

The dosage of Oxaliplatin concentrate for infusions is individualized based on body surface area and the specific protocol used. It is administered intravenously over a period of 2 hours.

Indications:

Oxaliplatin is indicated for the treatment of advanced colorectal cancer. It is often used in combination with other chemotherapy medications.

Contraindications:

This medication is contraindicated in patients with known hypersensitivity to oxaliplatin or any of the other ingredients. It should not be used in patients with pre-existing severe renal impairment.

Directions:

Oxaliplatin should only be administered by healthcare professionals experienced in the use of chemotherapy medications. It is important to follow the specific dosing and administration guidelines provided by the healthcare provider.

Scientific Evidence:

Oxaliplatin is a platinum-based chemotherapy drug that works by interfering with the DNA in cancer cells, ultimately leading to cell death. Studies have shown its efficacy in the treatment of colorectal cancer, both in the adjuvant and metastatic settings.

Clinical trials have demonstrated that oxaliplatin, when used in combination with other chemotherapy agents, can improve overall survival rates and progression-free survival in patients with colorectal cancer. Research published in the New England Journal of Medicine has highlighted the benefits of oxaliplatin-based regimens in the management of this disease.

Additional Information:

• Side effects: Common side effects of oxaliplatin may include peripheral neuropathy, nausea, and fatigue.
• Storage: Store Oxaliplatin concentrate for infusions in a refrigerator at 2°C to 8°C. Do not freeze.