Papalor (Pelargonium sidoides) oral drops 20 ml. №1

Description

Papalor composition
active substance: extract from the roots of pelargonium stonecrop (Pelargonium sidoides) (1:10), extractant – ethanol 15% (v / v);
1 g of solution contains an extract from the roots of Pelargonium sidoides (Pelargonium sidoides) (1:10), extractant – ethanol 15% (v / v), 800 mg;
excipient: glycerin.

Dosage form
Oral drops.

Pharmacological properties
Papalor is a herbal preparation containing an extract from the roots of the South African plant Pelargonium sidoides. The drug has a pronounced antiviral, antibacterial, immunomodulatory, mucolytic, cytoprotective effect, effective at all stages of the pathogenesis of acute respiratory viral infections, as well as prevents the progression and development of complications. The clinical effectiveness of the phytoextract is due to the action of the main components that are part of it: flavonoids (quercetin, halocatechin, kaempferol, etc.); coumarins (umcalin, scopolin, scopoletin, etc.), as well as phenolic acids (gallic acid, etc.).
The antibacterial activity of the drug is manifested against various gram-positive (Staphylococcus aureus, Streptococcus pneumoniae, beta-hemolytic Streptococcus) and gram-negative (Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Haemophilus influenzae) bacteria.
The effect on the nonspecific immune response is to stimulate the phagocytic activity of macrophages and release NO from them, increase the expression of CD11b-adhesion of molecules on the surface of neutrophils, inhibition of leukocyte chemotaxis. This indicates the immunomodulatory properties of the drug.
The drug activates the mechanisms of airway cleansing, which improves the excretion of viscous mucus and eliminates the conditions for the reproduction of pathogenic bacteria.
In addition, phenolic acids stimulate the endogenous system of antiviral protection, promote the synthesis of anti-inflammatory interleukins, interferon, protect cells from damage by infections, thereby showing a positive effect on the treatment process.

Indication
Acute and chronic infectious-inflammatory diseases of the respiratory tract and nasopharynx (bronchitis, catarrhal angina, sinusitis, rhinopharyngitis).

Contraindication
Hypersensitivity to the components of the drug; increased tendency to bleeding, taking drugs that slow down the blood clotting process; severe liver and kidney disease (due to lack of sufficient experience with this drug in such cases).

Children
There is no experience of using the drug in children under 1 year of age, so Papalor is prescribed to children from 1 year of age.
The use of Papalor for the treatment of young children (1 to 6 years) is recommended under medical supervision.

Use during pregnancy or breastfeeding
Due to the lack of experience in the use of Papalor, it is not recommended for use during pregnancy or breastfeeding.

Method of application and dosage
Papalor is taken orally half an hour before a meal. It is recommended to dilute the drug with a small amount of liquid before taking it.
Dosage regimen depending on age:

• 1 – 5 years 10 drops 3 times a day;
• 6 – 12 years 20 drops 3 times a day;
• Adults and children over 12 years of age 30 drops 3 times a day.

The duration of treatment is determined by the doctor individually.
After the symptoms have subsided, it is recommended to continue treatment with Papalor for a few more days to prevent recurrence. If the symptoms do not disappear within 7 days, it is recommended to see a doctor.

Overdose
To date, no cases of overdose have been reported. Possible aggravation of adverse reactions.

Side effects:

• From the digestive tract: disorders of the digestive tract (including stomach pain, heartburn, nausea, diarrhea), mild bleeding from the gums.
• From the respiratory system: weak nosebleeds.
• Skin / Immune system disorders: Hypersensitivity reactions (including skin rash, urticaria, itchy skin and mucous membranes). In very rare cases, severe hypersensitivity reactions with facial edema, shortness of breath and low blood pressure are possible.
• From the hepatobiliary system: increased liver function. A causal relationship between the increase in these rates and the use of the drug has not been demonstrated.

Expiration date
2 years.
Shelf life after opening the container is 3 months.

Storage conditions
Store at a temperature not exceeding 30 ° C.
Keep out of reach of children.