Description

Papaverin hydrochloride solution for injection 2% 2 ml. №10 vials

Ingredients

Each 2 ml vial contains 2% Papaverin hydrochloride solution for injection.

Dosage

The dosage should be determined by a healthcare professional based on individual needs. It is typically administered by injection into a muscle or vein as directed by a physician.

Indications

Papaverin hydrochloride solution is indicated for the treatment of smooth muscle spasms. It is commonly used to relieve spasms in the gastrointestinal tract, urinary system, and blood vessels.

Contraindications

Do not use Papaverin hydrochloride solution if you are allergic to any of the ingredients. It is also contraindicated in patients with severe hypotension or certain heart conditions.

Directions

Administer the injection as directed by a healthcare provider. Follow all instructions carefully and do not exceed the recommended dosage.

Scientific Evidence

Papaverin hydrochloride has been studied for its efficacy in treating smooth muscle spasms. Research has shown that it can effectively reduce spasms in various organs and systems of the body.

Additional Information

It is important to store Papaverin hydrochloride solution as directed and keep it out of reach of children. If you experience any adverse reactions, contact your healthcare provider immediately.

Pharmacological Effects: Papaverin hydrochloride acts as a smooth muscle relaxant by inhibiting the enzyme phosphodiesterase, leading to an increase in intracellular cyclic adenosine monophosphate (cAMP). This results in vasodilation and decreased smooth muscle contractions.

Clinical Trials: Clinical trials have demonstrated the effectiveness of Papaverin hydrochloride in various conditions, including biliary colic, renal colic, and peripheral vascular diseases. One study published in the Journal of Gastroenterology and Hepatology showed significant improvement in symptoms of irritable bowel syndrome with the use of Papaverin hydrochloride injections.