Description

Penciclovir-Fitofarm (penciclovir) cream 1% 5 g. tube

Ingredients

Active ingredient: Penciclovir 1%.
Inactive ingredients: [list of inactive ingredients].

Dosage

Apply a small amount of the cream to the affected area every 2 hours during waking hours for 4 days.

Indications

Penciclovir-Fitofarm cream is indicated for the treatment of recurrent herpes labialis (cold sores) in immunocompetent adults.

Contraindications

Do not use if allergic to penciclovir or any other ingredients in the cream.

Directions

Clean the affected area before applying the cream. Use a cotton swab or gloves to apply the cream to avoid spreading the infection.

Scientific Evidence

Penciclovir, the active ingredient in Penciclovir-Fitofarm cream, is a potent antiviral agent that works by inhibiting the replication of herpes simplex virus. Studies have shown that penciclovir is effective in reducing the duration of cold sore episodes and accelerating the healing process when compared to placebo or other antiviral treatments.

Additional Information

It is important to start treatment with Penciclovir-Fitofarm cream as soon as the first symptoms of a cold sore appear to maximize its effectiveness. Avoid applying the cream inside the mouth, eyes, or on mucous membranes. Consult a healthcare professional if the condition does not improve within 10 days of treatment.

Pharmacological Effects: Penciclovir inhibits viral DNA replication by competitively inhibiting viral DNA polymerase. This action prevents the virus from multiplying and spreading, ultimately reducing the severity and duration of cold sore outbreaks.

Clinical Trials: Clinical trials have demonstrated the efficacy of penciclovir in the treatment of recurrent herpes labialis. In a randomized controlled trial by Spruance et al., penciclovir cream was found to significantly reduce the duration of lesion healing compared to placebo, highlighting its effectiveness in managing cold sores.