Description

Pentilin (pentoxifylline) tablets 400 mg. №20

Ingredients:

Each tablet contains 400 mg of pentoxifylline as the active ingredient.

Dosage:

The usual dose is 1 tablet three times a day with meals.

Indications:

Pentilin is indicated for the treatment of peripheral vascular diseases. It helps improve blood flow and reduces the viscosity of blood, which can benefit patients with circulation issues.

Contraindications:

Do not use Pentilin if you have a history of bleeding disorders or recent stroke. It is important to consult a healthcare provider before starting this medication.

Directions:

Swallow the tablets whole with a full glass of water. Do not crush or chew the tablets. Follow the dosage instructions provided by your doctor.

Scientific Evidence:

Pentoxifylline, the active ingredient in Pentilin, has been extensively studied for its effects on peripheral vascular diseases. Research published in the Journal of Vascular Surgery demonstrated that pentoxifylline can improve walking distance in patients with intermittent claudication, a common symptom of peripheral artery disease.

Additional Information:

It is important to note that Pentilin may take several weeks to show its full effects. Patients should not exceed the recommended dosage without medical supervision to avoid potential side effects.

Pharmacological Effects:

Pentoxifylline works by increasing red blood cell flexibility and reducing blood viscosity, which helps enhance blood flow to the limbs. This improved circulation can relieve symptoms such as pain and cramping in patients with peripheral vascular diseases.

Clinical Trials and Comparative Effectiveness:

Clinical trials have shown that Pentilin is effective in improving symptoms and increasing walking distance in patients with peripheral artery disease when compared to placebo. Additionally, studies have suggested that Pentilin may have comparable efficacy to other vasodilator medications commonly used for peripheral vascular diseases.

Overall, Pentilin (pentoxifylline) tablets 400 mg. №20 offer a well-supported treatment option for individuals with peripheral vascular diseases, backed by scientific evidence and clinical trials.