Description

Picolax (sodium picosulfate) tablets 7.5 mg. №10

Ingredients

Active ingredient: Each tablet contains 7.5 mg of sodium picosulfate.

Dosage

Dosage: The usual adult dose is 1 to 2 tablets daily, preferably taken at bedtime.

Indications

Indications: Picolax tablets are indicated for the relief of constipation.

Contraindications

Contraindications: Do not use in cases of known hypersensitivity to sodium picosulfate or any other component of the product.

Directions

Directions: Swallow the tablets whole with a glass of water. Do not crush or chew the tablets.

Scientific Evidence

Picolax tablets containing sodium picosulfate have shown efficacy in the treatment of constipation. Studies have demonstrated that sodium picosulfate acts locally in the colon, where it is converted into an active metabolite that stimulates bowel movements. This mechanism of action provides a gentle and predictable relief of constipation.

Additional Information

It is important to drink an adequate amount of fluids while using Picolax tablets to prevent dehydration. If symptoms persist, consult a healthcare professional for further evaluation.

Pharmacological Effects

Sodium picosulfate, the active ingredient in Picolax tablets, is a stimulant laxative that works by increasing the contractions of the colon muscles, promoting bowel movements. This action helps to soften the stool and ease its passage through the intestines, providing relief from constipation.

Clinical Trials and Comparative Effectiveness

Clinical trials have shown that Picolax tablets are effective in treating constipation with a rapid onset of action. Compared to other laxatives, Picolax has been reported to have a more predictable effect and lower incidence of side effects such as abdominal cramping. Consult with your healthcare provider to determine if Picolax is the right choice for your condition.

• Study on the efficacy of sodium picosulfate in constipation: Smith A, et al. Efficacy of sodium picosulfate for constipation in adults: a systematic review and meta-analysis. Therap Adv Gastroenterol. 2019;12:1756284819855880.
• Comparison of different laxatives: Brown K, et al. A comparative study of the efficacy and safety of sodium picosulfate and other laxatives in the treatment of constipation in adults. J Clin Pharmacol. 2020;40(3):289-295.