Description

Plaquenil (hydroxychloroquine) Coated Tablets 200 mg. №60

Ingredients

Active ingredient: Hydroxychloroquine sulfate 200 mg. Other ingredients include lactose, magnesium stearate, and hydroxypropyl methylcellulose.

Dosage

Dosage: The usual adult dose for treating malaria is 800 mg initially, followed by 400 mg in 6-8 hours, then 400 mg daily for 2 consecutive days. For rheumatoid arthritis, the usual dose is 400-600 mg daily. Always follow your doctor’s instructions.

Indications

Indications: Plaquenil is indicated for the treatment of malaria, rheumatoid arthritis, and lupus erythematosus. It works by interfering with the communication between cells of the immune system.

Contraindications

Contraindications: Do not use Plaquenil if you are allergic to hydroxychloroquine or similar compounds. It is contraindicated in patients with retinal or visual field changes.

Directions

Directions: Take Plaquenil exactly as prescribed by your healthcare provider. It is usually taken with food or milk to prevent stomach upset. Do not crush or chew the tablets.

Scientific Evidence

Plaquenil has been extensively studied for its efficacy in treating various conditions. Research published in the “Journal of Rheumatology” has shown that hydroxychloroquine is effective in reducing disease activity and inflammation in patients with rheumatoid arthritis. Additionally, a study in the “Journal of the American Medical Association” demonstrated the drug’s effectiveness in preventing malaria.

Additional Information

Plaquenil’s pharmacological action involves inhibiting lysosomal activity and interfering with antigen presentation, leading to immunomodulatory effects. Clinical trials have shown that Plaquenil is well-tolerated and has a good safety profile compared to other disease-modifying antirheumatic drugs. It is considered a cornerstone in the management of autoimmune diseases.

Overall, Plaquenil (hydroxychloroquine) coated tablets 200 mg. №60 offer a reliable treatment option for malaria, rheumatoid arthritis, and lupus erythematosus. With a well-established scientific background and proven efficacy, this medication continues to be a valuable asset in managing various autoimmune conditions.