Prednizolon solution for injections 30 mg/ml. 1ml. ampoules №3

Description

Prednizolon Composition and release form
The main active ingredient is prednisone.
The drug goes on sale in the form of a suspension for the preparation of an injection solution, in ampoules, where 1 ml of the drug contains 30 mg of prednisolone.

Pharmacological properties
This drug Prednizolon belongs to the group of drugs from the group of glucocorticosteroids, which are used as an anti-inflammatory agent.
The main active ingredient is prednisone. It is a synthetic preparation, dehydrated analogue of hydrocortisone. Produces anti-inflammatory, anti-allergic, immunosuppressive effect. Has the ability to increase the resistance of beta-adrenergic receptors to endogenous catecholamines. It helps to reduce the level of globulin in blood plasma, reduces synthesis and increases the level of catabolism in muscle tissues. Promotes the redistribution of adipose tissue, enhances the absorption of carbohydrates from the gastrointestinal tract, and causes hyperglycemia. Retains sodium salts in the body.
Prevents the formation of scar tissue.

Indications
The specified pharmaceutical preparation Prednizolon is used for urgent treatment in cases where an immediate increase in the level of glucocorticosteroids in the body is required, if other means are ineffective.
In particular, when:

• a state of shock in case of burns, injuries, operations, intoxication, cardiogenic shocks;
• allergic reactions, especially in acute and severe forms of allergies – anaphylaxis, blood transfusion shock;
• cerebral edema, including brain tumors, surgery, radiation therapy, head trauma;
• bronchial asthma (severe attack), status asthmaticus;
• systemic connective tissue diseases (lupus erythematosus, rheumatoid arthritis);
• acute adrenal insufficiency;
• thyrotoxic crisis;
• acute hepatitis, hepatic coma;
• inflammation and prevention of scarring, including chemical burns.

Contraindications
The drug in question is contraindicated for use in cases where the patient has severe hypersensitivity (allergy) to the main or to one of the auxiliary components.
Also contraindicated for:

• stomach ulcer, gastritis, esophagitis, other diseases of the gastrointestinal tract;
• parasitic, fungal, bacterial and other infections;
• pre- and post-vaccination period;
• HIV AIDS;
• diabetes mellitus, thyrotoxicosis, hypothyroidism, and other diseases of the endocrine system;
• hypoalbuminemia;
• osteoporosis, glaucoma.

Children
It is contraindicated to use before reaching 18 years of age.

Application during pregnancy and lactation
During pregnancy, the use of this drug is contraindicated.
If there is a need to take the drug during lactation, then it should be suspended for the period of treatment.

Method of administration and dosage
This Prednizolon drug is injected – first by jet, then by drip. If intravenous administration is not possible, intramuscular administration is allowed. After the acute period has passed, they switch to oral administration of the drug.
The dosage depends on the disease, the patient’s condition.
A single dose usually ranges from 50 to 150 mg, a daily dose from 500 to 1200 mg per day. In some cases, the dose may be increased to 1400 per day.
The course of treatment is from 3 to 18 days.
The dosage is reduced gradually.
The duration of treatment, dosage and its correction are determined individually by the attending physician.

Overdose
Overdose can cause increased side effects.
In case of excessive ingestion, it is recommended to apply symptomatic treatment, to wash the stomach, and to take enterosorbents.

Side effects
When treating with this drug, side effects may occur in the form of allergic reactions – allergic urticaria, itching, rash, swelling, exanthema.
There are also possible side effects such as:

• diabetes mellitus, edema, dysmenorrhea, amenorrhea, increased blood pressure;
• nausea, vomiting, pancreatitis, stomach ulcer, fluctuations in appetite;
• arrhythmia, thrombosis;
• delirium, euphoria, insomnia, vertigo, convulsions;
• glaucoma, cataracts, loss of vision;
• hypocalcemia, sweating;
• hypernatremia, hypokalemia, myalgia, weakness;
• slowing growth;
• local reactions when administered intravenously;
• exacerbation or development of infections.

Storage conditions and periods
Shelf life – no more than 2 years from the date of issue indicated on the packaging by the manufacturer.
Storage temperature should not exceed 25 ° C.