Description

Pregabalin (pregabalin) capsules 75 mg. №14

Ingredients:

Each capsule contains 75 mg of pregabalin. Other ingredients include lactose monohydrate, maize starch, and talc.

Dosage:

The recommended dosage is 75 mg taken orally twice daily. Dosage may be adjusted based on individual response and tolerability.

Indications:

Pregabalin capsules are indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy. It is also used in the treatment of postherpetic neuralgia and for the adjunctive therapy for adults with partial onset seizures.

Contraindications:

Do not use pregabalin if you are allergic to pregabalin or any of the other ingredients in the capsule. It is contraindicated in patients with heart problems or those with a history of drug or alcohol abuse.

Directions:

Swallow the capsules whole with water. Do not crush or chew them. It can be taken with or without food, as directed by your healthcare provider.

Scientific Evidence:

Studies have shown that pregabalin is effective in reducing neuropathic pain and improving quality of life in patients with diabetic neuropathy. A study published in the American Journal of Medicine demonstrated that pregabalin significantly reduced pain scores compared to a placebo group.

Additional Information:

Pregabalin works by binding to calcium channels in the central nervous system, which reduces the release of neurotransmitters involved in pain signaling. It has a rapid onset of action and is generally well-tolerated. Clinical trials have also shown its efficacy in fibromyalgia and generalized anxiety disorder.

Compared to similar drugs, pregabalin has been found to have a more favorable side effect profile, with fewer incidences of sedation and cognitive impairment. It is considered a first-line treatment for neuropathic pain and is recommended in various clinical guidelines.