Description

Pregabalin-ZN (pregabalin) hard capsules 75 mg. №20

Ingredients

Each hard capsule contains 75 mg of pregabalin.

Dosage

The recommended dosage is as prescribed by a healthcare provider. It is typically taken orally, with or without food, usually twice a day.

Indications

Pregabalin is used to treat neuropathic pain, fibromyalgia, and certain types of seizures. It works by decreasing the number of pain signals that are sent out by damaged nerves in the body.

Contraindications

Do not use pregabalin if you are allergic to it or have certain types of heart problems. It is important to consult a healthcare provider before starting this medication.

Directions

Follow the directions provided by your doctor carefully. Do not increase or decrease the dose without consulting your healthcare provider.

Scientific Evidence

Studies have shown that pregabalin is effective in reducing neuropathic pain and improving quality of life in patients with fibromyalgia. Research published in the Journal of Pain Research highlighted the positive impact of pregabalin on pain relief and sleep quality in fibromyalgia patients.

Additional Information

It is important to be aware of the potential side effects of pregabalin, including dizziness, drowsiness, and weight gain. Regular monitoring by a healthcare provider is recommended to manage any adverse effects.

Pharmacological Effects: Pregabalin binds to calcium channels in the central nervous system, modulating the release of neurotransmitters involved in pain signaling. This mechanism helps in reducing neuropathic pain and improving pain control.

Clinical Trials: Clinical trials have demonstrated the efficacy of pregabalin in various conditions, including diabetic neuropathy and postherpetic neuralgia. A study published in Neurology showed significant pain reduction in diabetic neuropathy patients treated with pregabalin compared to a placebo group.