Description

Prenesa (perindopril tert-butylamine) tablets 8 mg. №90

Ingredients

Each tablet contains 8 mg of perindopril tert-butylamine.

Dosage

The recommended dosage is one tablet daily, or as directed by a healthcare professional.

Indications

Prenesa tablets are indicated for the treatment of hypertension and heart failure.

Contraindications

Do not use Prenesa if you are pregnant, have a history of angioedema related to previous ACE inhibitor therapy, or have severe renal impairment.

Directions

Take Prenesa tablets orally with or without food. Swallow the tablet whole with a glass of water.

Scientific Evidence

Prenesa (perindopril tert-butylamine) has been extensively studied in clinical trials for its efficacy in managing hypertension and heart failure. Research published in the Journal of Hypertension demonstrated that perindopril significantly reduced blood pressure compared to a placebo, highlighting its effectiveness in treating hypertension.

Additional Information

Prenesa works by inhibiting the angiotensin-converting enzyme (ACE), leading to vasodilation and reduced aldosterone secretion. This mechanism helps in lowering blood pressure and improving cardiac function in heart failure patients. Compared to other ACE inhibitors, Prenesa has shown similar efficacy but with a lower incidence of side effects, making it a favorable choice for many patients.

Clinical trials have also shown that Prenesa is well-tolerated, with a favorable safety profile. Patients taking Prenesa reported fewer incidences of cough and angioedema compared to other ACE inhibitors, enhancing its overall tolerability and adherence rates.