Description

Priora (docosanol) cream 100 mg/1g. 2 g. tube

Ingredients

Active ingredient: Docosanol 100 mg/g.
Other ingredients: Benzyl alcohol, light mineral oil, propylene glycol, purified water, stearyl alcohol, and white petrolatum.

Dosage

Apply a thin layer of Priora cream to the affected area 5 times a day, at approximately 3-hour intervals.
Do not exceed the recommended dosage.

Indications

Priora cream is indicated for the treatment of recurrent oral-facial herpes simplex outbreaks (cold sores) in immunocompetent adults and adolescents (12 years and older).

Contraindications

Do not use Priora cream if you are allergic to docosanol or any other ingredients in the product.

Directions

Wash your hands before and after applying Priora cream.
Apply the cream only to the affected area and avoid contact with eyes and mucous membranes.

Scientific Evidence

Docosanol, the active ingredient in Priora cream, works by inhibiting the fusion between the plasma membrane and the herpes simplex virus envelope, thereby preventing viral entry into healthy cells. Clinical studies have shown that docosanol can reduce the duration of cold sore symptoms when applied at the first sign of an outbreak.

Additional Information

Priora cream is for external use only.
Consult a healthcare professional if you are pregnant, breastfeeding, or have any underlying medical conditions before using Priora cream.

Pharmacological Effects: Docosanol exerts its antiviral effects by interfering with the viral entry process, specifically by inhibiting virus-cell membrane fusion. This mechanism prevents the virus from entering healthy cells and replicating, ultimately reducing the severity and duration of cold sore outbreaks.

Clinical Trials: Clinical trials have demonstrated the efficacy of docosanol in the treatment of cold sores. A study published in the Journal of the American Academy of Dermatology found that docosanol cream significantly reduced the healing time of cold sores compared to a placebo, highlighting its effectiveness in managing oral-facial herpes simplex outbreaks.