Description

Protopic (tacrolimus, mineral oil) Ointment 0.1% 10 g Tube

Ingredients

Active ingredients: Tacrolimus, Mineral Oil.

Dosage

Dosage: Apply a thin layer of the ointment to the affected skin twice daily. Consult a healthcare professional for specific instructions.

Indications

Indicated for: Protopic ointment is used to treat eczema (atopic dermatitis) in patients who cannot use other topical medications or have not responded to them.

Contraindications

Do not use Protopic if:

• You are allergic to tacrolimus or any other ingredients in the ointment.
• You have a skin infection in the area to be treated.

Directions

Directions for use: Wash your hands before and after applying the ointment. Apply a thin layer to the affected skin areas and rub in gently. Avoid covering the treated skin with bandages or dressings unless instructed by a healthcare provider.

Scientific Evidence

Protopic (tacrolimus) has been extensively studied in clinical trials for the treatment of atopic dermatitis. Research has shown that tacrolimus ointment is effective in reducing inflammation and controlling the symptoms of eczema, providing relief for patients with moderate to severe atopic dermatitis.

Pharmacological Effects: Tacrolimus works by inhibiting calcineurin, a protein that plays a key role in the immune response and inflammatory processes in the skin. By suppressing the activity of calcineurin, tacrolimus helps to reduce inflammation and relieve the symptoms of eczema.

Clinical Trials: Clinical studies have demonstrated the efficacy of Protopic ointment in the treatment of atopic dermatitis, showing significant improvements in disease severity, itching, and quality of life for patients. Compared to other topical treatments, Protopic has shown comparable effectiveness with a favorable safety profile.