Description

Ramizes (ramipril) tablets 2.5 mg. №30

Ingredients

Active ingredient: Ramipril 2.5 mg per tablet.

Dosage

Recommended dosage: The usual starting dose is 2.5 mg once daily. Dosage may be adjusted according to the individual patient’s response.

Indications

Ramizes tablets are indicated for the treatment of hypertension, heart failure, and to improve survival after a heart attack.

Contraindications

Do not use Ramizes tablets if:

• You are allergic to ramipril or any other ACE inhibitors.
• You have a history of angioedema related to previous ACE inhibitor therapy.
• You are pregnant, as it may cause harm to the fetus.

Directions

How to take: Swallow the tablet whole with a glass of water. It can be taken with or without food.

Scientific Evidence

Ramipril, the active ingredient in Ramizes tablets, is a well-studied ACE inhibitor with proven efficacy in the management of hypertension and heart failure. Clinical trials have demonstrated its ability to reduce cardiovascular events and improve outcomes in patients with heart disease. Research published in the New England Journal of Medicine has shown that ramipril significantly reduces the risk of myocardial infarction, stroke, and cardiovascular death in high-risk individuals.

Additional Information

Ramizes tablets should be stored at room temperature away from moisture and heat. It is important to regularly monitor blood pressure and kidney function while taking this medication. Consult your healthcare provider for personalized advice on dosage and potential side effects.

Pharmacological Effects

Ramipril works by inhibiting the angiotensin-converting enzyme (ACE), which plays a crucial role in regulating blood pressure and fluid balance in the body. By blocking ACE, ramipril helps to dilate blood vessels, reduce the workload on the heart, and improve blood flow. This mechanism of action leads to lowered blood pressure and improved cardiac function, making it an effective treatment for hypertension and heart failure.

Clinical Trials and Comparative Effectiveness

Numerous clinical trials have demonstrated the efficacy of ramipril in reducing cardiovascular events and mortality in patients with heart disease. In comparative studies, ramipril has shown similar or superior effectiveness compared to other ACE inhibitors in improving outcomes in heart failure and post-myocardial infarction patients. Its favorable safety profile and proven benefits make it a valuable option in the management of cardiovascular conditions.