Description
Ramizes (Ramipril) Tablets 2.5 mg. №30
Ingredients
Active ingredient: Each tablet contains Ramipril 2.5 mg.
Dosage
Recommended dosage: The usual starting dose is 2.5 mg once daily. Dosage may be adjusted based on the individual’s response.
Indications
Ramizes tablets are used to treat hypertension, heart failure, and improve survival post-heart attack.
Contraindications
- Do not use if allergic to ramipril or other ACE inhibitors.
- Avoid if a history of angioedema from previous ACE inhibitor therapy.
- Avoid during pregnancy due to potential harm to the fetus.
Directions
How to take: Swallow the tablet whole with water, with or without food.
Scientific Evidence
Ramipril, the active ingredient, is an ACE inhibitor studied for hypertension and heart failure. Clinical trials show reduced cardiovascular events and improved outcomes, especially in heart disease. Research in the New England Journal of Medicine indicates risk reduction in myocardial infarction, stroke, and cardiovascular death.
Additional Information
Store at room temperature away from moisture and heat. Monitor blood pressure and kidney function regularly while using. Seek healthcare provider advice for personalized guidance on dosage and potential side effects.
Pharmacological Effects
Ramipril inhibits angiotensin-converting enzyme (ACE), regulating blood pressure and fluid balance. By dilating blood vessels and reducing heart workload, it improves blood flow, lowers blood pressure, and enhances cardiac function, effective for hypertension and heart failure.
Clinical Trials and Comparative Effectiveness
Studies confirm ramipril’s efficacy in reducing cardiovascular events and mortality in heart disease patients. Compared to other ACE inhibitors, it shows similar or better effectiveness in heart failure and post-myocardial infarction cases. Its safety profile and benefits make it valuable in managing cardiovascular conditions.
