Description

Rezlod (dorzolamide) Eye Drops Solution 2% 5 ml. Bottle Dropper

Ingredients

Active ingredient: Dorzolamide 2%
Other ingredients: Benzalkonium chloride, hydroxyethyl cellulose, mannitol, sodium citrate, sodium hydroxide, and water.

Dosage

Dosage: Instill 1 drop in the affected eye(s) 3 times a day.

Indications

Indicated for: Lowering intraocular pressure in patients with ocular hypertension or open-angle glaucoma.

Contraindications

Contraindications: Hypersensitivity to dorzolamide or any component of the formulation.

Directions

Directions: Tilt your head back, pull down the lower eyelid, and instill the prescribed number of drops. Close your eye for 2 minutes without blinking.

Scientific Evidence

Dorzolamide, the active ingredient in Rezlod, is a carbonic anhydrase inhibitor that reduces intraocular pressure by decreasing aqueous humor production. Studies have shown its efficacy in lowering intraocular pressure and its role as an adjunctive therapy in glaucoma management.

Additional Information

Rezlod has been well-tolerated in clinical trials with minimal systemic side effects. It is important to inform your healthcare provider about any existing medical conditions or medications before using Rezlod to prevent potential drug interactions.

Pharmacological Effects: Dorzolamide inhibits carbonic anhydrase in the ciliary processes of the eye, reducing aqueous humor production and lowering intraocular pressure. This mechanism helps in the management of glaucoma and ocular hypertension.

Clinical Trials: Clinical trials have demonstrated the efficacy of dorzolamide in reducing intraocular pressure. A study by Realini et al. (2018) showed that dorzolamide, when used as an adjunctive therapy, significantly lowered intraocular pressure in patients with open-angle glaucoma.