Rinazal (xylometazoline hydrochloride) nasal drops 0.1% 10 ml. vial

Description

Rinazal (xylometazoline hydrochloride) nasal drops 0.1% 10 ml. vial

Composition 

active ingredient: xylometazoline;

1 ml of the drug contains xylometazoline hydrochloride 1 mg;

excipients: sodium hydrogen phosphate dodecahydrate, sodium dihydrogen phosphate dihydrate, sorbitol (E 420), decamethoxin, disodium edetate, purified water

Dosage form

Nasal drops, solution.

Basic physical and chemical properties: transparent colorless liquid.

Pharmacological group

Decongestants and other drugs for topical use in diseases of the nasal cavity. Sympathomimetics, simple drugs. Xylometazoline.
ATX code R01A A07.

Pharmacological properties

These are nasal drops. The active ingredient excites alpha-adrenergic receptors. When applied to the mucous membrane, it causes vasoconstriction, while reducing swelling, redness. With rhinitis (runny nose), relieves nasal breathing.

Indications

Rinazal is used for swelling of the nasal mucosa due to colds, rhinitis with a large amount of liquid mucous secretions (vasomotor rhinitis), as well as allergic rhinitis, acute sinusitis.
In addition, it is indicated for acute otitis media (to restore the patency of the Eustachian tube).

Contraindications

Rinazal nasal drops should not be used:

• with allergies to the components of the solution;
• with “dry” inflammation of the nasal mucosa with the formation of crusts (dry rhinitis);
• with the transferred transsphenoidal removal of the pituitary gland or any other surgical interventions with a history of exposure of the meninges;
• with tachycardia;
• with arterial hypertension;
• during pregnancy, breastfeeding;
• with simultaneous treatment with MAOIs, tricyclic antidepressants;
• children under one year old (drops 0.05%), children up to twelve years old (drops 0.1%).

Use with caution:

• when treating MAOIs or other drugs with a hypertensive effect in the past;
• with increased intraocular pressure, especially with angle-closure glaucoma;
• with cardiovascular pathology (for example, ischemic heart disease, arterial hypertension);
• with pheochromocytoma;
• with metabolic disorders (for example, diabetes mellitus, hyperthyroidism);
• with porphyria;
• with prostatic hyperplasia.

Application during pregnancy and lactation

During these periods, Rinazal is not used.

Method of administration and dosage

The bottle is sealed with a tamper evident seal. When using for the first time, it is necessary to turn the cap, separating it from the protective ring.

The bottle has a special configuration, thanks to which, when you press the bottom, a dosed release of the solution occurs according to the principle “one press – one drop”. The hardness of the walls of the vial significantly reduces the possibility of jet release of the drug – the most common cause of overdose of nasal drops.

Before the introduction of the drug, the nasal cavity should be thoroughly cleaned.

For adults and children over 12 years of age, use 2-4 drops in each nasal passage 3 times a day.

Apply no more than 3 times a day in each nasal passage (under adult supervision).

The duration of treatment depends on the course of the disease and should not exceed 10 consecutive days.

Children

Rinazal nasal drops 0.1% should not be used in children under 12 years of age.

For children, use the drug under the supervision of adults.

Overdose

When applied topically, overdose is unlikely.
Symptoms: mydriasis (dilated pupils), nausea, cyanosis, convulsions, fever, cardiovascular disorders (tachycardia, arterial hypertension, arrhythmia, cardiac arrest), respiratory failure, changes in consciousness, drowsiness, pulmonary edema, decreased body temperature, bradycardia (decrease heart rate), a sharp drop in blood pressure, respiratory arrest, coma development.
Overdose treatment: stopping treatment, seeking medical attention immediately, intensive care.

Side effects:

• Cardiovascular disorders: heart palpitations, arrhythmias, arterial hypertension.
• Neurological disorders: headache, paroxysm, insomnia, fatigue, dizziness.
• Respiratory, thoracic, mediastinal disorders: burning in the nose, feeling of dryness, shortness of breath, sneezing, increased swelling of the nasal mucosa, nosebleeds.
• General disorders: fatigue, drowsiness, visual impairment.
• Digestive disorders: nausea.
• Immune disorders: hypersensitivity reactions (angioedema, exanthema, itching).
• Mental disorders: sleep disturbances, agitation, hallucinations.