Rinazolin (oxymetazoline) nasal spray 0.05% 15 ml. vial

Description

Rinazolin (oxymetazoline) nasal spray 0.05% 15 ml. vial

Composition

active ingredient: oxymetazoline;

1 ml of solution contains oxymetazoline hydrochloride in terms of 100% substance 0.5 mg;

excipients: benzalkonium chloride, polyethylene glycol, sodium dihydrogen phosphate dihydrate, disodium phosphate dodecahydrate, propylene glycol, povidone, purified water.

Dosage form

Spray nasal.

Basic physical and chemical properties: transparent colorless or slightly yellowish liquid.

Pharmacological group

Decongestants and other drugs for topical use in diseases of the nasal cavity. Sympathomimetics.
Code ATX R01A A05.

Pharmacological properties

Rinazolin nasal spray belongs to the group of local vasoconstrictors. Oxymetazoline has a sympathomimetic and vasoconstrictive effect, eliminating swelling of the nasal mucosa. It constricts blood vessels at the site of application, reduces swelling of the nasal mucosa and upper respiratory tract, and reduces nasal discharge. Restores nasal breathing. Elimination of swelling of the nasal mucosa helps to restore aeration of the paranasal sinuses, the middle ear cavity, which prevents the development of bacterial complications.

Oxymetazoline has antiviral, anti-inflammatory, immunomodulatory and antioxidant effects. This combined mechanism of action has been shown in clinical studies to provide faster and more effective relief from the symptoms of acute rhinitis (nasal congestion, rhinorrhea, sneezing, feeling unwell).

Indications:

• Acute respiratory diseases accompanied by nasal congestion.
• allergic rhinitis.
• Vasomotor rhinitis.
• To restore drainage and nasal breathing in diseases of the paranasal sinuses, eustachitis.
• To eliminate edema before diagnostic manipulations in the nasal passages.

Contraindications:

• Hypersensitivity to the components of the drug.
• Atrophic rhinitis.
• Do not use after transsphenoidal hypophysectomy or other surgical interventions with exposure of the meninges.
• When using monoamine oxidase (MAO) inhibitors and within 2 weeks after stopping treatment with MAO inhibitors, as well as other drugs that increase blood pressure.
• With increased intraocular pressure, especially with angle-closure glaucoma.
• In severe forms of cardiovascular disease (for example, coronary heart disease, arterial hypertension).
• Pheochromocytoma.
• Metabolic disorders (hyperthyroidism, diabetes mellitus).
• Hyperplasia of the prostate.
• Porfiry.

Application during pregnancy and lactation

During the indicated periods, Rinazolin is used with extreme caution. Do not exceed the recommended doses.

Method of administration and dosage

Immediately before using the drug, the bottle should be held in the palm of your hand to warm it to body temperature. Before the introduction of the drug, you need to thoroughly clean the nose. When using the bottle, hold it vertically, spray up. Before use, remove the protective cap of the bottle, place the tip of the nozzle in the nasal passage, squeeze the bottle with a short sharp movement and, removing the tip from the nose, unclench. During the injection, it is recommended to inhale a little through the nose.

Adults and children over the age of 6 years – 1 injection in each nasal passage 2-3 times a day. A single dose should not be used more than 3 times a day and more than 5-7 days. Do not use doses higher than recommended.

The drug can be used again only after a few days.

Children

Assign to children from 6 years.

Overdose

Abuse of this pharmaceutical agent leads to atrophy of the nasal mucosa and medication rhinitis.
After a significant overdose of Rinazolin or its accidental ingestion, symptoms such as cyanosis (cyanosis), mydriasis (dilated pupils) or miosis (narrowing of the pupils), nausea, drowsiness, fever, fever, agitation, vomiting, tachycardia, pallor, arterial hyper- / hypotension, spasms, arrhythmia, pulmonary edema, hyperhidrosis (increased sweating), respiratory distress, mental disorders, convulsions. Also possible are cardiovascular failure, apnea (respiratory arrest), coma, cardiac arrest.
In case of an overdose with Rinazolin, gastric lavage, the use of enterosorbents, symptomatic and supportive therapy are indicated. If necessary, artificial lung ventilation, anticonvulsant therapy is performed.

Side effects

Side effects due to the use of Rinazolin include nasal discomfort, headache, nosebleeds, drowsiness, sneezing, dryness or burning of the nasal mucosa, convulsions, fatigue, arterial hypertension, tachycardia.
It is also possible to develop allergic reactions (including angioedema).
When the effect of using Rinazolin ends, you may experience a feeling of severe nasal congestion.