Rint with menthol (oxymetazoline) nasal spray 0.5 mg/g. 10 g. vial

$14.00

Manufacturer: Ukraine

Acute respiratory diseases accompanied by nasal congestion. Allergic rhinitis. Vasomotor rhinitis. To restore drainage and nasal breathing in diseases of the paranasal sinuses of the nasal cavity, Eustachian. To eliminate edema before diagnostic manipulations in the nasal passages.

Description

Rint with menthol (oxymetazoline) nasal spray 0.5 mg/g. 10 g. vial

Composition

active substance: oxymetazoline;

1 ml of the drug contains 0.5 mg of oxymetazoline hydrochloride based on 100% dry matter;

auxiliary substances: racemic camphor, menthol (levomenthol), benzalkonium chloride, disodium edetate (Trylon B), benzyl alcohol, polyethylene glycol 400 (macrogol 400), povidone, sodium carboxymethyl cellulose – microcrystalline cellulose, sodium dihydrogen phosphate, dihydrate; sodium hydrogen phosphate, dodecahydrate; water for injections.

Medicinal form

Nasal spray.

Main physicochemical properties: opaque, whitish, gel-like liquid or solution with a specific smell and thixotropic properties (thickens when standing and thins when shaken).

Pharmacotherapeutic group

Anti-edematous and other drugs for local use in diseases of the nasal cavity. Sympathomimetics, simple drugs.
ATX code R01A A05.

Pharmacological properties

This is a nasal spray. The active ingredient excites alpha-adrenergic receptors. When applied to the mucous membrane, it causes vasoconstriction, while reducing swelling, redness. With rhinitis (runny nose), relieves nasal breathing.

Indications

Rint is used for swelling of the nasal mucosa due to colds, coryza attacks with a large amount of liquid mucous secretions (vasomotor rhinitis), as well as allergic rhinitis, acute sinusitis.
In addition, it is indicated for acute otitis media (to restore the patency of the Eustachian tube).
It is also used to facilitate rhinoscopy.

Contraindications

Rint should not be used:

  • with allergies to the components of the solution;
  • with “dry” inflammation of the nasal mucosa with the formation of crusts (dry rhinitis);
  • with the transferred transsphenoidal removal of the pituitary gland or any other surgical interventions with a history of exposure of the meninges;
  • with tachycardia;
  • with arterial hypertension;
  • with angina pectoris;
  • with severe atherosclerosis;
  • during pregnancy, breastfeeding;
  • with simultaneous treatment with MAOIs, tricyclic antidepressants;
  • children under six years old.

Use with caution:

  • when treating MAOIs or other drugs with a hypertensive effect in the past;
  • with increased intraocular pressure, especially with angle-closure glaucoma;
  • with cardiovascular pathology;
  • with pheochromocytoma;
  • with metabolic disorders (for example, diabetes mellitus, hyperthyroidism);
  • with porphyria;
  • with prostatic hyperplasia.

Application during pregnancy and lactation

During these periods, Rint is not used.

Method of administration and dosage

Rint is applied intranasally (into the nose).
The spray is used in children from 6 years of age and in adults – one injection into each nasal passage up to three times a day.
It is not recommended to use the spray for more than five days.

Overdose

When applied topically, overdose is unlikely.
Symptoms: mydriasis (dilated pupils), nausea, cyanosis, convulsions, fever, cardiovascular disorders (tachycardia, arterial hypertension, arrhythmia, cardiac arrest), respiratory failure, changes in consciousness, drowsiness, pulmonary edema, decreased body temperature, bradycardia (decrease heart rate), a sharp drop in blood pressure, respiratory arrest, coma development.
Overdose treatment: stopping treatment, seeking medical attention immediately, intensive care.

Side effects:

  • Cardiovascular disorders: heart palpitations, arrhythmias, arterial hypertension.
  • Neurological disorders: headache, paroxysm, insomnia, fatigue, dizziness.
  • Respiratory, thoracic, mediastinal disorders: burning sensation in the nose, feeling of dryness, shortness of breath, sneezing, increased swelling of the nasal mucosa, epistaxis, atrophy of the nasal mucosa.
  • General disorders: tachyphylaxis, fatigue, drowsiness, visual impairment.
  • Digestive disorders: nausea.
  • Immune disorders: hypersensitivity reactions (angioedema, exanthema, itching).
  • Mental disorders: sleep disturbances, agitation, hallucinations.