Description

Rint with Menthol (Oxymetazoline) Nasal Spray 0.5 mg/g. 10 g. Vial

Ingredients

Active ingredient: Oxymetazoline hydrochloride 0.5 mg/g. Other ingredients include menthol, benzalkonium chloride, disodium edetate, sodium dihydrogen phosphate dihydrate, and purified water.

Dosage

Adults and children over 6 years: 1-2 sprays into each nostril every 10-12 hours, not exceeding 2 doses in 24 hours. Do not use for more than 3 consecutive days.

Indications

Rint with Menthol Nasal Spray is indicated for the relief of nasal congestion associated with allergies, hay fever, sinusitis, and the common cold.

Contraindications

Do not use if: allergic to oxymetazoline or any other ingredients, taking MAO inhibitors, have heart disease, high blood pressure, thyroid disease, diabetes, or prostate enlargement.

Directions

Shake well before use. Clear nasal passages before spraying. Tilt head slightly forward and insert nozzle into nostril. Spray and inhale gently. Repeat for the other nostril. Avoid spraying into eyes.

Scientific Evidence

Oxymetazoline, the active ingredient in Rint with Menthol Nasal Spray, is a sympathomimetic agent that works by constricting blood vessels in the nasal passages, reducing swelling and congestion. Studies have shown its efficacy in providing rapid relief from nasal congestion with minimal systemic absorption and side effects.

Additional Information

It is important to follow the recommended dosage and duration of use to avoid rebound congestion. Consult a healthcare professional before use if pregnant, breastfeeding, or have any underlying medical conditions. Keep out of reach of children.

Pharmacological effects of oxymetazoline include vasoconstriction, which leads to decreased nasal congestion. The drug acts on alpha-adrenergic receptors in the nasal mucosa, resulting in the constriction of blood vessels and reduction of nasal blood flow. This mechanism helps alleviate congestion and improves breathing.

Clinical trials have demonstrated the effectiveness of oxymetazoline nasal sprays in providing relief from nasal congestion in various conditions. A study by Eccles et al. (2015) showed that oxymetazoline provided significant and rapid relief from nasal congestion compared to placebo, highlighting its efficacy in managing nasal symptoms.