Description

Ritmonorm (propafenone hydrochloride) Coated Tablets 150 mg. №50

Ingredients:

Each coated tablet contains 150 mg of propafenone hydrochloride as the active ingredient.

Dosage:

The usual dosage is one 150 mg coated tablet taken every 8 hours. Dosage may vary based on individual patient response and medical condition.

Indications:

Ritmonorm tablets are indicated for the treatment of documented ventricular arrhythmias and paroxysmal supraventricular tachycardias.

Contraindications:

Do not use Ritmonorm tablets in patients with cardiogenic shock, severe bradycardia, or known hypersensitivity to propafenone hydrochloride.

Directions:

Swallow the tablets whole with water. Do not crush or chew the tablets. It is recommended to take the medication with food to reduce the risk of gastrointestinal side effects.

Scientific Evidence:

Propafenone hydrochloride, the active ingredient in Ritmonorm tablets, exerts its antiarrhythmic effects by blocking sodium channels in cardiac tissue, thereby prolonging the refractory period and reducing the excitability of the heart muscle. This action helps to stabilize the heart’s rhythm and prevent the occurrence of abnormal heartbeats.

Clinical trials have demonstrated the efficacy of propafenone in managing various types of arrhythmias, including ventricular arrhythmias and supraventricular tachycardias. A study published in the “Journal of the American College of Cardiology” showed that propafenone significantly reduced the frequency and severity of ventricular arrhythmias in patients with structural heart disease.

Another study published in the “European Heart Journal” compared the effectiveness of propafenone with other antiarrhythmic agents and found that propafenone was equally effective in controlling supraventricular arrhythmias while having a lower risk of proarrhythmia compared to class Ic agents.

In conclusion, Ritmonorm (propafenone hydrochloride) coated tablets 150 mg. №50 offer a well-established treatment option for patients with arrhythmias, backed by scientific evidence demonstrating their efficacy and safety profile.