Description

RizaMigren (rizatriptan) tablets 5 mg. №3

Ingredients

Active ingredient: Rizatriptan benzoate 5 mg.

Dosage

Dosage: The recommended dose is one tablet (5 mg) at the first sign of a migraine headache. Do not exceed 2 doses in a 24-hour period.

Indications

Indications: RizaMigren is indicated for the acute treatment of migraine attacks with or without aura.

Contraindications

Contraindications: Do not use RizaMigren if you have uncontrolled hypertension, ischemic heart disease, or have used MAO inhibitors in the past 14 days.

Directions

Directions: Swallow the tablet whole with water. Do not crush, chew, or break the tablet.

Scientific Evidence

Rizatriptan, the active ingredient in RizaMigren, is a selective 5-HT1 receptor agonist that has been shown to effectively relieve migraine symptoms by constricting blood vessels in the brain. Clinical studies have demonstrated that rizatriptan provides rapid and significant pain relief compared to placebo, making it a valuable option for migraine management.

Additional Information

It is important to note that RizaMigren is not intended for the prevention of migraines and should only be used to treat acute migraine attacks. If you experience chest pain, tightness in the chest, or throat, or have symptoms of a heart attack after taking RizaMigren, seek immediate medical attention.

Pharmacological Effects

Rizatriptan works by binding to serotonin receptors in the brain, leading to the constriction of blood vessels and the inhibition of pro-inflammatory neuropeptide release. This action helps alleviate the pain and other symptoms associated with migraines. Additionally, rizatriptan has been shown to reduce the incidence of migraine-associated symptoms such as nausea and sensitivity to light and sound.

Clinical Trials and Comparative Effectiveness

Clinical trials have demonstrated the efficacy of rizatriptan in providing rapid and sustained relief from migraine symptoms. In comparative studies, rizatriptan has shown similar effectiveness to other triptans in relieving pain and improving quality of life in migraine patients. Its quick onset of action and tolerability make it a preferred choice for many individuals suffering from migraines.

Overall, RizaMigren (rizatriptan) tablets 5 mg. №3 offer a scientifically supported and effective treatment option for individuals experiencing acute migraine attacks.