Description
Rizoptan (Rizatriptan) Tablets 10 mg. №6
Ingredients
- Active ingredient: Rizatriptan benzoate 10 mg.
Dosage
- Dosage: The recommended dose is one tablet (10 mg) at the first sign of a migraine headache. Do not exceed 2 doses in a 24-hour period.
Indications
- Indications: Rizoptan is indicated for the acute treatment of migraine attacks with or without aura.
Contraindications
- Contraindications: Do not use Rizoptan if you have uncontrolled hypertension, ischemic heart disease, or have taken ergotamine or its derivatives within the last 24 hours.
Directions
- Directions: Swallow the tablet whole with water. It can be taken with or without food.
Scientific Evidence
Rizatriptan, the active ingredient in Rizoptan, is a selective 5-HT1B/1D receptor agonist known for its vasoconstrictive properties in the treatment of migraines. Studies have shown that rizatriptan effectively relieves migraine symptoms, including pain, nausea, and sensitivity to light and sound, within 2 hours of administration.
Additional Information
- Pharmacological Effects: Rizatriptan works by binding to serotonin receptors in the brain, causing vasoconstriction of the blood vessels involved in migraine headaches. This action helps to reduce inflammation and pain associated with migraines.
- Clinical Trials: Clinical trials have demonstrated the efficacy of Rizoptan in providing rapid relief from migraine symptoms. In a randomized, double-blind study published in the Journal of Headache and Pain, rizatriptan was found to be significantly more effective than placebo in relieving pain and associated symptoms of migraines.
