Description

Rizoptan (rizatriptan) tablets 10 mg. №6

Ingredients

Active ingredient: Rizatriptan benzoate 10 mg.

Dosage

Dosage: The recommended dose is one tablet (10 mg) at the first sign of a migraine headache. Do not exceed 2 doses in a 24-hour period.

Indications

Indications: Rizoptan is indicated for the acute treatment of migraine attacks with or without aura.

Contraindications

Contraindications: Do not use Rizoptan if you have uncontrolled hypertension, ischemic heart disease, or have taken ergotamine or its derivatives within the last 24 hours.

Directions

Directions: Swallow the tablet whole with water. It can be taken with or without food.

Scientific Evidence

Rizatriptan, the active ingredient in Rizoptan, is a selective 5-HT1B/1D receptor agonist known for its vasoconstrictive properties in the treatment of migraines. Studies have shown that rizatriptan effectively relieves migraine symptoms, including pain, nausea, and sensitivity to light and sound, within 2 hours of administration.

Additional Information

Rizoptan tablets have been well-tolerated in clinical trials, with the most common side effects being dizziness, fatigue, and dry mouth. It is important to consult a healthcare provider before using this medication, especially if you have a history of cardiovascular disease or risk factors for stroke.

Pharmacological Effects: Rizatriptan works by binding to serotonin receptors in the brain, causing vasoconstriction of the blood vessels involved in migraine headaches. This action helps to reduce inflammation and pain associated with migraines.

Clinical Trials: Clinical trials have demonstrated the efficacy of Rizoptan in providing rapid relief from migraine symptoms. In a randomized, double-blind study published in the Journal of Headache and Pain, rizatriptan was found to be significantly more effective than placebo in relieving pain and associated symptoms of migraines.