Rhizostin (sodium risedronate) coated tablets 35 mg. №4

Description

Rhizostin (sodium risedronate) coated tablets 35 mg. №4

Composition

active substance: sodium risedronate;

1 tablet contains 35 mg of risedronate sodium in the form of risedronate sodium hemipentahydrate;

auxiliary substances: colloidal anhydrous silicon dioxide, maltodextrin, mannitol (E 421), povidone, pregelatinized starch, sodium starch glycolate (type A), sodium stearyl fumarate, anhydrous ethanol;

tablet shell: sucrose, triethyl citrate, titanium dioxide (E 171), iron oxide yellow (E 172), iron oxide red (E 172), talc, ethanol anhydrous, polyvinyl alcohol – polyethylene glycol graft copolymer.

Medicinal form

Coated tablets.

The main physical and chemical properties:

tablets in the form of a modified capsule with an orange shell, on one side of the tablet imprint “RS”, on the other – “35”.

Pharmacotherapeutic group

Means affecting the structure and mineralization of bones. Bisphosphonates.
ATX code M05B A07.

Pharmacological properties

Rhizostin refers to drugs that affect bone mineralization and structure. Osteoporosis leads to a decrease in bone mass, which is the cause of an increased risk of fractures of the neck of the hip, spine and wrist. This disease can occur in both men and women, especially during menopause. The use of the drug helps to reduce the level of bone resorption, increase the mineral density of bone tissue.

Indications for use

Rhizostin is used and prescribed to treat postmenopausal osteoporosis to reduce the risk of vertebral and femoral fractures, as well as osteoporosis in men at high risk of fractures.

Contraindications

The drug Rhizostin has almost no contraindications. Do not use the drug in severe renal failure, hypocalcemia, hypersensitivity to the components and in childhood.

Pregnancy and breastfeeding

The use of the drug Rhizostin in pregnant women and nursing mothers is contraindicated.

Method of application

The drug Rhizostin is intended for oral administration.
The recommended dose is 35 mg (1 tablet) once a week.
The tablets are taken on the same day of the week, half an hour before meals, on an empty stomach, without chewing, drinking plenty of water. While taking the drug and 30 minutes after, the patient should be in an upright position.

Overdose

No cases of Rizostin overdose have been reported. At intoxication with drug development of signs of a hypocalcemia and decrease in calcium in blood is possible.
As a treatment, the patient can be given antacids or milk, if more than half an hour has passed since the overdose, it is recommended to rinse the stomach.

Adverse reactions

The use of the drug Rhizostin can lead to side effects such as:
headache, liver dysfunction, joint, muscle and bone pain, dyspepsia, constipation, nausea, diarrhea, duodenitis, abdominal pain, esophagitis, dysphagia, gastritis, esophageal ulcers, uveitis and inflammation of the iris.
Taking the drug can cause: decreased levels of phosphates and calcium,
hypersensitivity reactions and skin reactions, including angioneurotic edema, urticaria, generalized rash.
Also possible: osteonecrosis of the lower jaw, diaphyseal fractures and atypical femoral sciatica, hair loss and anaphylactic reactions.
In the event of any adverse reactions, it is necessary to cancel the drug and consult a doctor for further use.