Rolinoz (cetirizine) oral drops solution 10 mg/ml. 20 ml. vial

Description

Rolinoz (cetirizine) oral drops solution 10 mg/ml. 20 ml. vial

Composition

active substance: cetirizine;

1 ml of solution (20 drops) contains cetirizine dihydrochloride 10 mg;

excipients: glycerin (85%); propylene glycol; sodium saccharin; methylparaben (E 218); propylparaben (E 216); sodium acetate, trihydrate; glacial acetic acid; the water is purified.

Medicinal form

Oral drops.

Main physical and chemical properties: transparent colorless liquid.

Pharmacotherapeutic group

Antihistamines for systemic use. Piperazine derivatives.
ATX code R06A E07.

Pharmacological properties

Cetirizine, a metabolite of hydroxyzine, is a potent selective antagonist of peripheral H1 receptors. In vitro receptor binding studies showed no significant affinity for receptors other than H1 receptors.

Indications

Rolinoz oral dropsis an anti-allergic medicine. Its active substance is a blocker of H1-histamine receptors.
This medication is prescribed to eliminate nasal (nasal), eye symptoms of persistent (year-round) or intermittent (seasonal) allergic rhinitis, allergic conjunctivitis (nasal congestion, conjunctival redness, itching in the nose / eyes, sneezing, watery eyes). It can also be used for chronic idiopathic urticaria.

Contraindications

You cannot appoint Rolinoz oral drops:

• with allergies to components;
• at the terminal stage of renal failure (with an indicator of creatinine clearance;
• during pregnancy;
• for tablets: with rare forms of galactose intolerance, Lapp lactase deficiency, glucose / galactose malabsorption.

It is used with caution:

• with old age;
• with a predisposition to urinary retention;
• with chronic kidney disease (with a creatinine clearance rate> 10 ml / minute) – dosage adjustment is required;
• with epilepsy, increased convulsive readiness;
• during lactation.

Application during pregnancy and lactation

No cases of the formation of malformations, embryonic, neonatal toxicity with a clear causal relationship have been identified. However, there have been no strictly controlled studies, therefore this medication should not be used during pregnancy.
The medicine can penetrate into breast milk, therefore, feeding is stopped during treatment.

Method of administration and dosage

It is administered orally (by mouth), regardless of food.
Children aged 2–6 years: the medicine is used in the form of drops of 2.5 mg (5 drops) x2 times / day.
Adults, children over 6 years of age: daily dose – 10 mg (20 drops or 1 tablet) once (preferably at night).
An initial dose of 5 mg (10 drops or half a tablet) can be used if sufficient to control symptoms.

Overdose

Overdose symptoms: confusion, increased fatigue, diarrhea, dizziness, headache, itching, malaise, dilated pupils, anxiety, drowsiness, weakness, stupor, frequent heartbeat, tremors, urinary retention.
Overdose treatment: immediately after administration – gastric lavage (or stimulation of vomiting), intake of sorbent (activated carbon), maintenance and symptomatic therapy.

Side effects

Possible allergic reactions (angioedema, urticaria, rash, itching, persistent drug erythema), increased appetite, thrombocytopenia (decreased platelet count), agitation, confusion, depression, aggression, hallucinations, sleep disturbances, nervous tics, suicidal ideation, movement disorders , paresthesia, convulsions, taste perversion, fainting, trembling, memory impairment, impaired accommodation, nystagmus (wobbling of the eyes), blurred vision, dizziness, heart palpitations, loose stools, liver dysfunctions, changes in liver function tests, urinary disturbances (urinary retention, enuresis ), malaise, swelling, weight gain.