Description

Rolinoz (cetirizine) tablets 10 mg. №20

Ingredients

Active ingredient: Cetirizine 10 mg per tablet.

Dosage

Adults and children over 6 years: Take 1 tablet once daily with or without food.

Indications

Rolinoz tablets are indicated for the relief of symptoms associated with seasonal and perennial allergic rhinitis, such as sneezing, runny nose, itchy and watery eyes, and itching of the nose or throat.

Contraindications

Do not use Rolinoz tablets if:

• You are allergic to cetirizine or any other ingredients in the product.
• You have severe kidney impairment.
• You are pregnant or breastfeeding without consulting a healthcare provider.

Directions

Swallow the tablet whole with a full glass of water. Do not chew or crush the tablet. Follow the dosage instructions provided unless otherwise directed by a healthcare professional.

Scientific Evidence

Cetirizine, the active ingredient in Rolinoz tablets, is a second-generation antihistamine that selectively inhibits peripheral H1 receptors. Studies have shown that cetirizine is effective in relieving allergic symptoms with a low incidence of sedation compared to first-generation antihistamines.

Additional Information

It is important to note that cetirizine may cause drowsiness in some individuals. Avoid driving or operating heavy machinery until you know how this medication affects you. If you experience any severe or persistent side effects, discontinue use and consult a healthcare professional.

Pharmacological Effects

Cetirizine works by blocking the action of histamine, a substance in the body that causes allergic symptoms. By inhibiting the histamine receptors, cetirizine helps reduce the symptoms of allergic reactions, such as itching, sneezing, and runny nose. It has a rapid onset of action and provides long-lasting relief.

Clinical Trials and Comparative Effectiveness

Clinical trials have demonstrated the efficacy of cetirizine in the treatment of allergic rhinitis and chronic urticaria. In comparative studies, cetirizine has shown similar effectiveness to other second-generation antihistamines with a favorable side effect profile. Research published in the Journal of Allergy and Clinical Immunology supports the use of cetirizine as a first-line treatment for allergic conditions.

Investigating the pharmacokinetics and pharmacodynamics of cetirizine, a study published in the European Journal of Clinical Pharmacology highlighted its safety and efficacy profile, making it a preferred choice in the management of allergic diseases.

Always consult a healthcare professional before starting any new medication regimen.