Description

Sermion (nicergoline) Lyophilisate for Solution for Injection 4 mg. 4 ml. Vials №4 with Solvent

Ingredients:

Each vial contains 4 mg of nicergoline as the active ingredient. Other ingredients include lyophilisate and solvent components.

Dosage:

The recommended dosage is determined by a healthcare professional based on individual patient needs. It is typically administered via injection as directed.

Indications:

Sermion is indicated for the treatment of cognitive disorders of vascular origin. It helps improve blood flow to the brain, potentially enhancing cognitive function.

Contraindications:

Do not use Sermion if you are allergic to nicergoline or any of the other ingredients. It is important to consult with a healthcare provider before starting this medication.

Directions:

Follow the instructions provided by your healthcare provider for the correct administration of Sermion. It is typically given as an injection and should not be self-administered without proper training.

Scientific Evidence:

Nicergoline, the active ingredient in Sermion, has been studied for its effects on cognitive function and cerebral blood flow. Research published in the journal *Clinical Drug Investigation* demonstrated the efficacy of nicergoline in improving cognitive performance in patients with mild to moderate cognitive impairment. Additionally, a meta-analysis published in *CNS Drugs* highlighted the potential benefits of nicergoline in enhancing cerebral blood flow, which is crucial for brain function.

Additional Information:

It is important to note that Sermion should be used as part of a comprehensive treatment plan for cognitive disorders under the supervision of a healthcare professional. While individual responses to the medication may vary, it is essential to adhere to the prescribed dosage and follow-up appointments for optimal outcomes.

Pharmacological Effects: Nicergoline acts as a vasodilator, improving blood flow in the brain by dilating blood vessels. This mechanism of action helps enhance oxygen and nutrient delivery to brain cells, potentially improving cognitive function.

Clinical Trials: Clinical trials have shown promising results regarding the efficacy of nicergoline in the treatment of cognitive disorders. A study published in *International Clinical Psychopharmacology* reported significant improvements in cognitive function and overall clinical status in patients receiving nicergoline compared to placebo.