Description

Sertofen (dexketoprofen) solution for injections 50 mg/2 ml. 2 ml. ampoules №5

Ingredients:

Each 2 ml ampoule contains 50 mg of dexketoprofen trometamol as the active ingredient.

Dosage:

The recommended dosage is one ampoule (50 mg) administered via intramuscular injection every 8 hours as needed.

Indications:

Sertofen is indicated for the management of moderate to severe pain. It is commonly used postoperatively or in conditions such as musculoskeletal pain and dental pain.

Contraindications:

Do not use Sertofen if you have a history of hypersensitivity to dexketoprofen or other NSAIDs. It is contraindicated in patients with active peptic ulcers, severe heart failure, or renal impairment.

Directions:

Administer Sertofen via deep intramuscular injection. Do not exceed the recommended dosage or duration of treatment. Always follow the instructions provided by your healthcare provider.

Scientific Evidence:

Dexketoprofen, the active ingredient in Sertofen, is a nonsteroidal anti-inflammatory drug (NSAID) with potent analgesic and anti-inflammatory properties. Studies have shown that dexketoprofen provides effective pain relief with a rapid onset of action. Research published in the Journal of Pain Research demonstrated the efficacy of dexketoprofen in managing acute postoperative pain.

Additional Information:

It is important to monitor for signs of gastrointestinal bleeding, renal impairment, and cardiovascular events while using Sertofen. Avoid concomitant use with other NSAIDs or anticoagulants without medical advice.

Dexketoprofen works by inhibiting the enzyme cyclooxygenase, thereby reducing the production of prostaglandins that are involved in the inflammatory response and pain perception. This dual mechanism of action makes it a valuable option for the treatment of pain and inflammation.

Comparative studies have shown that dexketoprofen offers similar efficacy to other NSAIDs but with a potentially lower risk of gastrointestinal side effects. Its favorable safety profile and rapid onset of action make it a preferred choice in the management of acute pain conditions.