Description
Sirdalud (Tizanidine) Tablets 4 mg. №30
Ingredients:
Each tablet contains 4 mg of tizanidine hydrochloride as the active ingredient.
Dosage:
The usual starting dose is 2 mg to 4 mg taken every 6 to 8 hours as needed.
Indications:
Sirdalud tablets are indicated for the management of spasticity associated with neurological conditions such as multiple sclerosis, spinal cord injury, or stroke.
Contraindications:
Do not use Sirdalud if you are allergic to tizanidine or if you are taking fluvoxamine.
Directions:
Swallow the tablets whole with a full glass of water. Do not crush, chew, or break the tablets.
Scientific Evidence:
Tizanidine, the active ingredient in Sirdalud, acts as a centrally acting alpha-2 adrenergic agonist. It exerts its muscle relaxant effects by inhibiting the release of excitatory neurotransmitters in the spinal cord, leading to a reduction in muscle tone.
- Studies have shown the efficacy of tizanidine in reducing muscle spasticity and improving functional outcomes in patients with neurological disorders.
- Research published in the Journal of Neurology, Neurosurgery, and Psychiatry demonstrated a significant reduction in muscle tone and improvement in muscle spasms in patients with multiple sclerosis compared to placebo.
- Another study in the European Journal of Physical and Rehabilitation Medicine found that tizanidine effectively reduced spasticity in individuals with spinal cord injury.
Additional Information:
- Pregnancy and Lactation: Consult your doctor before using Sirdalud if you are pregnant, planning to become pregnant, or breastfeeding.
- Side Effects: Common side effects may include drowsiness, dizziness, and dry mouth. Notify your healthcare provider if these side effects persist or worsen.
