Description

SMOFlipid (soybean oil refined) 20% emulsion for infusions 100 ml. vial №1

Ingredients:

SMOFlipid 20% emulsion for infusions contains refined soybean oil, medium-chain triglycerides, olive oil, and fish oil.

Dosage:

The recommended dosage of SMOFlipid is determined by the patient’s energy requirements and clinical status. It is administered intravenously over a specific period as directed by a healthcare professional.

Indications:

SMOFlipid is indicated for parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or contraindicated. It provides essential fatty acids and calories to support the patient’s nutritional needs.

Contraindications:

Do not use SMOFlipid in patients with hypersensitivity to egg, fish, soybean, or any other component of the product. It is also contraindicated in patients with severe liver insufficiency.

Directions:

Administer SMOFlipid under the supervision of a healthcare provider experienced in the use of parenteral nutrition. Monitor patients for signs of hypersensitivity reactions during infusion.

Scientific Evidence:

Studies have shown that SMOFlipid is well-tolerated and effective in providing essential fatty acids and nutrients in patients requiring parenteral nutrition. Research by Klek S. et al. (2016) demonstrated the safety and efficacy of SMOFlipid in critically ill patients.

Additional Information:

SMOFlipid offers a balanced lipid profile that mimics natural dietary fat, reducing the risk of essential fatty acid deficiency. It has a lower risk of inducing liver steatosis compared to other lipid emulsions, making it a preferred choice in clinical practice.

Pharmacologically, SMOFlipid provides a source of calories and essential fatty acids, supporting cell membrane integrity, hormone production, and inflammatory response modulation. The balanced composition of soybean, MCT, olive, and fish oils ensures a comprehensive lipid profile for optimal nutrition.

Clinical trials comparing SMOFlipid to other lipid emulsions have shown comparable efficacy in meeting nutritional requirements and improving clinical outcomes. The unique composition of SMOFlipid offers advantages in terms of tolerability and reduced risk of complications, making it a valuable option in parenteral nutrition therapy.