Description

Spazmalgon (metamizole, pitofenone) tablets №10

Ingredients

Active ingredients: Metamizole, Pitofenone

Dosage

Dosage: The usual dose is 1-2 tablets taken orally up to 3 times a day. Do not exceed the recommended dosage.

Indications

Indications: Spazmalgon tablets are indicated for the relief of moderate to severe pain associated with smooth muscle spasms.

Contraindications

Contraindications: Do not use Spazmalgon if you are allergic to any of the ingredients, have a history of blood disorders, or are pregnant.

Directions

Directions: Swallow the tablets whole with a glass of water. Do not crush or chew the tablets.

Scientific Evidence

Spazmalgon combines the analgesic properties of metamizole with the smooth muscle relaxant effects of pitofenone to provide effective pain relief. Studies have shown that metamizole is a potent analgesic with antispasmodic effects, while pitofenone acts directly on smooth muscle to reduce spasms.

Additional Information

Spazmalgon tablets have been clinically proven to be effective in the management of conditions such as renal colic, biliary colic, and dysmenorrhea. The combination of metamizole and pitofenone offers a synergistic effect, providing rapid and long-lasting relief from pain and muscle spasms.

Pharmacological Effects: Metamizole works by inhibiting prostaglandin synthesis, which plays a key role in the generation of pain and inflammation. Pitofenone acts as a calcium channel blocker, relaxing smooth muscles and reducing spasms.

Clinical Trials: A randomized controlled trial published in the Journal of Pain Research demonstrated the superior efficacy of Spazmalgon in comparison to other analgesics in the management of acute abdominal pain. The study highlighted the rapid onset of action and sustained pain relief provided by Spazmalgon.