Sulfargyn (silver sulfadiazine) ointment 1% 50 g. tube

$27.00

Manufacturer: Latvia

Prevention of infection and treatment of infected burns, pressure sores, ulcers, superficial wounds with weak exudation, abrasions; skin transplantation.

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Description

Sulfargyn (silver sulfadiazine) ointment 1% 50 g. tube

Composition

active substance: silver sulfadiazine;

1 g of ointment contains 10 mg of silver sulfadiazine;

Excipients: mineral oil, propylene glycol, cetostearyl alcohol, glycerol monostearate, polysorbate 80, methylparaben (E 218), propylparaben (E 216), purified water.

Dosage form

Ointment.

Main physical and chemical properties: ointment white or almost white, with a characteristic odor.

Pharmacotherapeutic group

Antibacterial and chemotherapeutic agents used in dermatology. Sulfanilamides.
ATX code D06B A01.

Pharmacological properties

Silver sulfadiazine has an antimicrobial effect on gram-positive and gram-negative microbes and fungi (Candida, Phycomycetes and Aspergillus spp, dermatophytes). The activity of the ointment is based on silver ions, which are released in the wound as a result of moderate dissociation of silver sulfadiazine, which achieves long-term antimicrobial action, which complements sulfadiazine (sulfanilamide). Silver ions are adsorbed on the surface of microbial cells and have a so-called oligodynamic bacteriostatic and bactericidal action. The ointment does not have necrolytic and mutagenic effects, is characterized by moderate osmotic activity.

Indications

Sulfargyn ointment is used for prophylactic and therapeutic purposes, for the treatment of purulent wounds and burns, trophic ulcers, as well as bedsores, skin transplantation, which are characterized by a slowdown in healing due to tissue trophic disorders. Sulfargin is effective in the treatment in the first phase of injury, with mild discharge, and is also used to treat fresh burns of the 1st – 3rd degree and the 3rd phase of the wound process, including stump wounds (remnant of an amputated limb).
Sulfadiazine has an antimicrobial effect on gram-positive and gram-negative microbes and mycoses (fungus). The effectiveness of sulfadiazine is due to the antimicrobial ability of silver ions, which harmoniously complements sulfonamides. Silver ions are adsorbed on the surface of microbial cells and have a bacteriostatic effect. The ointment has no necrolytic or mutagenic properties and is characterized by moderate osmotic activity.

Contraindications

It is forbidden to use for the treatment of children under 3 months of age, including premature babies, who are allergic to sulfonamide drugs, as well as for the treatment of wounds with abundant fluid secretion (exudation) and patients with porphyria.

Application during pregnancy and lactation

Prohibited for use.

Method of administration and dosage

Apply Sulfargyn ointment to the wound surface with a thin layer twice a day. The wound is pretreated with antiseptics, removing the remnants of dead (necrotic) tissue. It is permissible to leave the wound open, or cover it with a gauze bandage. Do not exceed the maximum dose of the drug (0.3 g per application). The duration of the course of treatment (3 weeks) should not be exceeded.
The final decision on the type and duration of treatment is made by the attending physician.

Overdose

There have been no cases of drug overdose. If accidentally swallowed, rinse the stomach.

Side effects

The occurrence of such side effects that are characteristic of the use of drugs with a sulfonamide composition, in particular, burning, pain, skin necrosis, contact dermatitis, allergic asthma attacks, may occur, nausea, vomiting, diarrhea, convulsions, crystalluria, glossitis (inflammation of the tongue), joint pain, thrombocytopenia, eosinophilia, the number of leukocytes in the blood may also decrease, and argyria may develop (discoloration of the skin due to excessive ingestion of silver cells into the body). Abundant intake of alkaline liquids is recommended.