Description

Tavegyl (clemastine) tablets 1 mg. №20

Ingredients

Active ingredient: Clemastine 1 mg per tablet.

Dosage

Adults: Take 1 tablet (1 mg) orally once a day.
Children: Consult a healthcare provider for appropriate dosage.

Indications

Tavegyl tablets are indicated for the relief of symptoms associated with allergic conditions such as hay fever, hives, and allergic skin reactions.

Contraindications

Do not use Tavegyl tablets if you are allergic to clemastine or any other ingredients in the product. Consult a healthcare provider before use if pregnant or breastfeeding.

Directions

Take Tavegyl tablets orally with or without food. Do not crush or chew the tablets. Follow the dosage instructions provided by your healthcare provider.

Scientific Evidence

Clemastine, the active ingredient in Tavegyl tablets, is a first-generation antihistamine that works by blocking the action of histamine in the body. Histamine is a substance in the body that is involved in allergic reactions, causing symptoms like itching, sneezing, and watery eyes. Several studies have demonstrated the effectiveness of clemastine in relieving these symptoms.

Additional Information

It is important to note that while Tavegyl tablets can provide relief from allergy symptoms, they may cause drowsiness. Avoid driving or operating heavy machinery until you know how this medication affects you. If you experience any severe side effects or have concerns about using Tavegyl, consult your healthcare provider.

Pharmacological Effects

Clemastine, the active ingredient in Tavegyl tablets, exerts its pharmacological effects by selectively antagonizing the H1 histamine receptors. By blocking these receptors, clemastine inhibits the action of histamine, thereby reducing the symptoms of allergic reactions. Additionally, clemastine has anticholinergic properties, contributing to its therapeutic effects in allergic conditions.

Clinical Trials and Comparative Effectiveness

Clinical trials have shown that clemastine, the key component of Tavegyl tablets, is effective in the management of allergic conditions. In comparative studies, clemastine has demonstrated similar efficacy to other first-generation antihistamines in alleviating allergy symptoms. However, its sedative effects may vary among individuals, warranting personalized treatment approaches.

References:
1. Simons FE. Comparative pharmacology of H1 antihistamines: clinical relevance. Am J Med. 2002 Mar 18;113 Suppl 9A:38S-46S.