Tebocan (ginkgo biloba) coated tablets 120 mg. №20

Description

Tebocan (ginkgo biloba) coated tablets 120 mg. №20

Composition

active substance: dry ginkgo biloba leaf extract (EGb 761) (Ginkgo biloba L., folium);

1 film-coated tablet contains Ginkgo biloba leaf extract (EGb 761) (35-67: 1), extractant: acetone 60% (w / w) 120 mg, standardized to 26.4-32.4 mg of flavonoids in the form of flavonoid glycosides; 6.48–7.92 mg of terpenlactones, of which 3.36–4.08 mg – ginkgolides A, B and C and 3.12–3.84 mg of whitebalide and not more than 0.6 μg of ginkgolic acids;

Excipients: lactose monohydrate, microcrystalline cellulose, corn starch, colloidal anhydrous silica, croscarmellose sodium, magnesium stearate, hypromellose, macrogol 1500, titanium dioxide (E 171), iron oxide red, eluate red and emu (E 172) dimethicone, colloidal anhydrous silica, α-octadecyl-ω-hydroxypoly (oxyethylene) -5, sorbic acid.

Dosage form

Film-coated tablets.

Main physical and chemical properties: red, round smooth, coated tablets.

Pharmacotherapeutic group

Remedies for dementia.
ATX code N06D X02.

Pharmacological properties

It is a herbal remedy that normalizes cell metabolism. It also improves the rheological properties of blood, microcirculation, cerebral circulation, delivery of glucose and oxygen to the brain. Prevents aggregation of erythrocytes, inhibits platelet activating factor. In addition, it reveals a regulatory effect on the vascular system (dose-dependent), stimulates the production of an endothelium-dependent dilating factor, increases venous tone, dilates small arteries, regulating blood circulation in the vessels. Reduces the permeability of the vascular wall, has an antithrombotic effect, prevents the formation of free radicals, lipid peroxidation of cell membranes. Normalizes re-absorption, catabolism, release of neurotransmitters (dopamine, norepinephrine, acetylcholine), their ability to bind to receptors. It improves metabolism in tissues, has an antihypoxic effect, helps to increase the utilization of oxygen, glucose, accumulation of macroergs in cells, and normalizes mediator processes in the brain.

Indications

Tebocan is applied:

• with neurosensory deficiency of various origins (diabetic retinopathy, senile macular degeneration);
• with cognitive deficits of various origins (traumatic brain injury, discirculatory encephalopathy after a stroke, old age), which is manifested by a decrease in intellectual abilities, impaired attention, memory, fear, sleep disturbance);
• with intermittent claudication as a result of chronic obliterating arteriopathies of the lower extremities (grade II according to Fontaine);
• with visual impairment of vascular origin, a decrease in its acuity;
• with hearing impairment, vertigo, tinnitus, impaired coordination of vascular genesis;
• with Raynaud’s syndrome.

Contraindications

Do not use Tebocan in case of hypersensitivity to ginkgo biloba extract, any component of the drug.

Application during pregnancy and lactation

Not recommended.

Method of administration and dosage

Tebocan is used internally.
The standard dose is one tablet 1-2 times / day. The average duration of treatment is 3 months.
For cognitive impairments – one tablet 1-2 times / day. The duration of treatment is at least eight weeks.
For peripheral occlusive arterial disease, dizziness of vascular / involutional origin – one tablet 1-2 times / day. The duration of treatment is at least eight weeks.
With dizziness, the duration of treatment is no more than 6–8 weeks, with tinnitus – at least 12 weeks.

Overdose

No data available. There may be an increase in the manifestations of side effects. In case of an overdose, symptomatic treatment is prescribed.

Side effects:

• Neurological disorders: headache, fainting (including vasovagal), dizziness.
• Digestive disorders: dyspeptic symptoms, abdominal pain, nausea, diarrhea.
• Immune disorders: angioedema, shortness of breath, urticaria, rashes.
• Dermatological disorders: itching, skin inflammation, edema, redness, rash, eczema.
• Others: hemorrhages (in the eye, gastrointestinal, in the brain).