Description
Tingrex (Memantine) Coated Tablets 10 mg. №60
Ingredients
- Active ingredient: Memantine hydrochloride
- Inactive ingredients: Microcrystalline cellulose, colloidal silicon dioxide, talc, magnesium stearate, hypromellose, titanium dioxide, polyethylene glycol
Dosage
Recommended dosage: The usual starting dose is 5 mg once daily, then increased by 5 mg weekly. Maximum dose is 20 mg per day.
Indications
Indicated for: Treatment of moderate to severe Alzheimer’s disease.
Contraindications
Do not use Tingrex if: Allergic to memantine or any ingredients, severe kidney problems, pregnant, or breastfeeding.
Directions
Administration: Swallow whole with water, with or without food. Do not crush, chew, or break the tablet.
Scientific Evidence
Memantine, the active ingredient, regulates glutamate activity, aiding cognitive function and Alzheimer’s disease progression. Studies show efficacy in improving cognitive function and daily living activities in Alzheimer’s patients.
Additional Information
Follow prescribed dosage, avoid exceeding recommended amount. May cause dizziness or drowsiness; caution when operating machinery or driving. Consult before use, especially with medical conditions or other medications.
Pharmacological Effects
Memantine acts as an NMDA receptor antagonist, modulating glutamate levels to protect brain cells from excessive stimulation, unique in Alzheimer’s treatment.
Clinical Trials and Comparative Effectiveness
Memantine improves cognitive function, behavior, and overall functioning in Alzheimer’s patients with favorable side effect profile. Studies show comparable efficacy to other medications. Well-tolerated and effective in managing symptoms.
