Tirozur (tyrothricin) gel 1 mg/g. 5 g. tube

Description

Tirozur (tyrothricin) gel 1 mg/g. 5 g. tube

Composition

active substance: thyrotricin,

1 g of gel contains 1 mg of thyrotricin;

Excipients: cetylpyridinium chloride, propylene glycol, ethanol 96%, carbomer, trometamol, purified water.

Dosage form

Gel.

Main physical and chemical properties: colorless opalescent viscous gel.

Pharmacotherapeutic group

Antibiotics for topical use.
ATX code D06A X08.

Pharmacological properties

This drug Tirozur gel belongs to the group of antibacterial agents used topically.
The main active ingredient is the antibiotic tyrothricin. Refers to compounds of polypeptides of both cyclic and linear properties. These peptides have high antibacterial activity. Tyrothricin in the process of transformation becomes a spore-forming endotoxin, which contains 70-80% tyrocidins and 20-30% gramicidins. Affects both gram-positive (hemophilic bacteria, nesseria meningitus, corynebacteria, diplococci, etc.) and gram-negative, as well as some mycobacteria, including the genus “Candida”. The bactericidal mechanism of action is associated with the ability of tyrothricin to destroy the osmotic barriers of cell membranes in pathological bacteria. It also causes the bacteria cells to lose potassium, which also shortens their lifespan.
When applied topically, the drug helps to accelerate wound healing, accelerating their epithelialization.

Indications

The specified medical agent is used for local treatment of external wounds, violations of the integrity of the skin, other tissues, characterized by a slight release of exudate and the presence of superinfection, which are caused by pathogenic microorganisms sensitive to tyrothricin.
In particular, it accelerates the healing of lacerations, scratches, abrasions.

Contraindications

The drug Tirozur gel in question is contraindicated for use in cases where the patient has severe hypersensitivity (allergy) to the main or to one of the auxiliary components.
It should not be used intranasally (applied to the mucous membrane of the nose, its wings), as this can cause a violation of the sense of smell.
Application of the drug to the area around the eyes should be done with great care, because this can cause burning and itching of the eyes.
Before use, be sure to read the full instructions for the drug attached by the manufacturer.
It can be used in pediatrics from the moment of birth.

Application during pregnancy and lactation

The drug should not be administered during pregnancy.
If there is a need to use this drug during lactation, breastfeeding should be suspended for this period.

Method of administration and dosage

The drug Tirozur gel is used topically, applying the gel 2-3 times a day to the affected areas.
The gel is applied in a thin layer, capturing intact skin areas.
It is not necessary to cover a small area of ​​the wound.
In case of extensive damage or profusely weeping wounds, a protective bandage should be applied on top. It is not removed for 1-2 days.
The duration of the disease depends on the individual reaction to the drug, the patient’s condition and is established by the attending physician.
If no improvement occurs within 7 days, then the drug is canceled.

Overdose

Overdose has not been observed at the moment and is unlikely with the correct use of the drug.
Side effects
When treating with this drug, side effects may occur only in case of manifestation of an individual intolerance to the drug.
In particular, there may be:

• nausea, diarrhea, vomiting;
• allergic urticaria, erythema, contact dermatitis, burning sensation;
• other manifestations of allergic reactions.