Description

Tolperil (tolperisone) Coated Tablets 50 mg. №30

Ingredients:

Each coated tablet contains 50 mg of tolperisone.

Dosage:

The recommended dosage is one 50 mg coated tablet three times a day.

Indications:

Tolperil tablets are indicated for the relief of muscle spasms and stiffness. It is commonly used in conditions such as muscle spasticity, back pain, and musculoskeletal disorders.

Contraindications:

Do not use Tolperil tablets if you are allergic to tolperisone or any other ingredients in the product. It is also contraindicated in patients with severe hepatic or renal impairment.

Directions:

Swallow the tablet whole with a glass of water. Do not crush or chew the tablet. It can be taken with or without food, as directed by your healthcare provider.

Scientific Evidence:

Studies have shown that tolperisone, the active ingredient in Tolperil tablets, acts centrally on the spinal cord and brainstem to exert its muscle relaxant effects. Research published in the Journal of Pain Research demonstrated the efficacy of tolperisone in reducing muscle tone and improving muscle function in patients with musculoskeletal disorders.

Additional Information:

• Storage: Store at room temperature away from moisture and heat.
• Side Effects: Common side effects may include dizziness, drowsiness, and dry mouth.
• Precautions: Inform your doctor about any existing medical conditions or medications before using Tolperil tablets.

Pharmacological Effects: Tolperisone exerts its muscle relaxant effects by modulating the calcium influx into muscle cells, leading to decreased muscle contractions and improved muscle function. It also has mild analgesic properties, providing additional pain relief benefits.

Clinical Trials: In a randomized controlled trial published in the European Journal of Physical and Rehabilitation Medicine, tolperisone was found to be effective in reducing muscle spasticity and improving functional outcomes in patients with neurological disorders.